Evidence map›Paper›PMID 32357913›Full record

ArticleTrials2020

Effects of perioperative enhanced recovery after surgery pathway management versus traditional management on the clinical outcomes of laparoscopic-assisted radical resection of distal gastric cancer: study protocol for a randomized controlled trial.

Yulong Tian, Shougen Cao, Leping Li, Qingsi He, Lijian Xia, Lixin Jiang, Yinlu Ding, Xinjian Wang, Hao Wang, Weizheng Mao and 6 more

Abstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yulong TianDepartment of Gastrointestinal Surgery, Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao, China.
Shougen CaoDepartment of Gastrointestinal Surgery, Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao, China.
Leping LiDepartment of Gastrointestinal Surgery, Shandong Provincial Hospital, Jinan, China.
Qingsi HeDepartment of Gastrointestinal Surgery, Qilu Hospital of Shandong University, Jinan, China.
Lijian XiaDepartment of Gastrointestinal Surgery, Qianfoshan Hospital of Shandong Province, Jinan, China.
Lixin JiangDepartment of Gastrointestinal Surgery, Yantai Yuhuangding Hospital, Yantai, China.
Yinlu DingDepartment of Gastrointestinal Surgery, Second Hospital of Shandong University, Jinan, China.
Xinjian WangDepartment of Gastrointestinal Surgery, Weihai Central Hospital, Weihai, China.
Hao WangDepartment of Gastrointestinal Surgery, Dongying People's Hospital, Dongying, China.
Weizheng MaoDepartment of Gastrointestinal Surgery, Qingdao Municipal Hospital, Qingdao, China.
Xizeng HuiDepartment of Gastrointestinal Surgery, Rizhao People's Hospital, Rizhao, China.
Yiran ShiDepartment of Oncological Surgery, Weifang People's Hospital, Weifang, China.
Huanhu ZhangDepartment of Gastrointestinal Surgery, Weihai Municipal Hospital, Weihai, China.
Xianqun ChuDepartment of Gastrointestinal Surgery, Jining People's Hospital, Jining, China.
Henrik KehletSection of Surgical Pathophysiology 4074, Rigshospitalet Copenhagen University, Copenhagen, Denmark.
Yanbing ZhouDepartment of Gastrointestinal Surgery, Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao, China. zhouyanbing999@aliyun.com.

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 81572314
6 · The paper itself

Abstract

backgroundThe incidence of gastric cancer in East Asia is much higher than the international average. Therefore, improving the prognosis of patients and establishing effective clinical pathways are important topics for the prevention and treatment of gastric cancer. At present, the enhanced recovery after surgery (ERAS) pathway is widely used in the field of gastric surgery. Many randomized controlled trial (RCT) studies have proven that the ERAS regimen can improve the short-term clinical outcomes of patients with gastric cancer. However, a prospective study on the effect of the ERAS pathway on the prognosis of patients with gastric cancer has not yet been reported. This trial aims to confirm whether the ERAS pathway can improve the disease-free survival and overall survival of patients undergoing laparoscopic-assisted radical resection for distal gastric cancer. METHODS/

designThis study is a prospective, multicentre RCT. This experiment will consist of two groups - an experimental group and a control group - randomly divided in a 1:1 ratio. The perioperative period of the experimental group will be managed according to the ERAS pathway and that of the control group will be managed according to the traditional management mode. An estimated 400 patients will be enrolled. The main endpoint for comparison is the 3-year overall survival and disease-free survival between the two groups. DISCUSSION: The results of this RCT should clarify whether the ERAS pathway is superior to traditional treatment on inflammatory indexes, short-term clinical outcome and survival for laparoscopic-assisted radical resection of distal gastric cancer. It is hoped that our data will provide evidence that the ERAS pathway improves survival in patients with gastric cancer.

trial registrationChinese Clinical Trial Registry, CHiCTR1900022438. Registered on 11 April 2019.

Indexed as

Enhanced Recovery After SurgeryAdenocarcinomaAdolescentAdultAgedDisease-Free SurvivalEvaluation Studies as TopicFemaleFollow-Up StudiesGastrectomyHumansLaparoscopyLength of StayMaleMiddle AgedMulticenter Studies as TopicClinical outcomesERAS pathwayGastric cancerLaparoscopic distal gastrectomyRandomized controlled trialTraditional treatment

Identifiers

PMID32357913
PMCPMC7193340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.