Evidence map›Paper›PMID 32357903›Full record

ArticleTrials2020

Peer support for people with severe mental illness versus usual care in high-, middle- and low-income countries: study protocol for a pragmatic, multicentre, randomised controlled trial (UPSIDES-RCT).

Galia S Moran, Jasmine Kalha, Annabel S Mueller-Stierlin, Reinhold Kilian, Silvia Krumm, Mike Slade, Ashleigh Charles, Candelaria Mahlke, Rebecca Nixdorf, David Basangwa and 10 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

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  11. Virtual nurse support to enhance antipsychotic adherence in schizophrenia: A South African perspective.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 6 countries.

Galia S MoranThe Charlotte B. and Jack J. Spitzer Department of Social Work, Ben Gurion University of the Negev, Be'er Sheva, Israel. galiam@bgu.ac.il.ORCID http://orcid.org/0000-0001-9718-1773
Jasmine KalhaCentre for Mental Health Law and Policy, Indian Law Society, Pune, India.
Annabel S Mueller-StierlinDepartment of Psychiatry and Psychotherapy II, Ulm University, Ulm, Germany.
Reinhold KilianDepartment of Psychiatry and Psychotherapy II, Ulm University, Ulm, Germany.
Silvia KrummDepartment of Psychiatry and Psychotherapy II, Ulm University, Ulm, Germany.
Mike SladeSchool of Health Sciences, Institute of Mental Health, University of Nottingham, Nottingham, UK.
Ashleigh CharlesSchool of Health Sciences, Institute of Mental Health, University of Nottingham, Nottingham, UK.
Candelaria MahlkeDepartment of Psychiatry, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Rebecca NixdorfDepartment of Psychiatry, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
David BasangwaButabika National Referral Hospital, Kampala, Uganda.
Juliet NakkuButabika National Referral Hospital, Kampala, Uganda.
Richard MpangoButabika National Referral Hospital, Kampala, Uganda.
Grace RyanCentre for Global Mental Health, London School of Hygiene and Tropical Medicine, London, UK.
Donat ShambaIfakara Health Institute, Dar es Salaam, Tanzania.
Mary RameshIfakara Health Institute, Dar es Salaam, Tanzania.
Fileuka NgakongwaIfakara Health Institute, Dar es Salaam, Tanzania.
Alina GrayzmanThe Charlotte B. and Jack J. Spitzer Department of Social Work, Ben Gurion University of the Negev, Be'er Sheva, Israel.
Soumitra PathareCentre for Mental Health Law and Policy, Indian Law Society, Pune, India.
Benjamin MayerInstitute for Medical Biometry and Epidemiology, Ulm University, Ulm, Germany.
Bernd PuschnerDepartment of Psychiatry and Psychotherapy II, Ulm University, Ulm, Germany.
Universität Ulm · DEButabika Hospital · UGIfakara Health Institute · TZBen-Gurion University of the Negev · ILIndian Law Institute · INUniversität Hamburg · DEUniversity of Nottingham · GBLondon School of Hygiene & Tropical Medicine · GB

Funding

Horizon 2020 Framework Programme 779263
6 · The paper itself

Abstract

backgroundPeer support is an established intervention involving a person recovering from mental illness supporting others with mental illness. Peer support is an under-used resource in global mental health. Building upon comprehensive formative research, this study will rigorously evaluate the impact of peer support at multiple levels, including service user outcomes (psychosocial and clinical), peer support worker outcomes (work role and empowerment), service outcomes (cost-effectiveness and return on investment), and implementation outcomes (adoption, sustainability and organisational change).

methodsUPSIDES-RCT is a pragmatic, parallel-group, multicentre, randomised controlled trial assessing the effectiveness of using peer support in developing empowering mental health services (UPSIDES) at four measurement points over 1 year (baseline, 4-, 8- and 12-month follow-up), with embedded process evaluation and cost-effectiveness analysis. Research will take place in a range of high-, middle- and low-income countries (Germany, UK, Israel, India, Uganda and Tanzania). The primary outcome is social inclusion of service users with severe mental illness (N = 558; N = 93 per site) at 8-month follow-up, measured with the Social Inclusion Scale. Secondary outcomes include empowerment (using the Empowerment Scale), hope (using the HOPE scale), recovery (using Stages of Recovery) and health and social functioning (using the Health of the Nations Outcome Scales). Mixed-methods process evaluation will investigate mediators and moderators of effect and the implementation experiences of four UPSIDES stakeholder groups (service users, peer support workers, mental health workers and policy makers). A cost-effectiveness analysis examining cost-utility and health budget impact will estimate the value for money of UPSIDES peer support. DISCUSSION: The UPSIDES-RCT will explore the essential components necessary to create a peer support model in mental health care, while providing the evidence required to sustain and eventually scale-up the intervention in different cultural, organisational and resource settings. By actively involving and empowering service users, UPSIDES will move mental health systems toward a recovery orientation, emphasising user-centredness, community participation and the realisation of mental health as a human right.

trial registrationISRCTN, ISRCTN26008944. Registered on 30 October 2019.

Indexed as

Global HealthMental HealthPeer GroupAdolescentAdultCost-Benefit AnalysisCounselingCrisis InterventionFemaleFollow-Up StudiesGermanyHumansIndiaIsraelMaleMental DisordersCost-effectiveness analysisGlobal mental healthImplementation sciencePeer supportPragmatic randomised controlled trialProcess evaluationSevere mental illness

Identifiers

PMID32357903
PMCPMC7195705
OpenAlexW3023876784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.