Evidence map›Paper›PMID 32357270›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2020

Alcohol Consumption and Risk of Parkinson's Disease: Data From a Large Prospective European Cohort.

Susan Peters, Valentina Gallo, Paolo Vineis, Lefkos T Middleton, Lars Forsgren, Carlotta Sacerdote, Sabina Sieri, Andreas Kyrozis, María-Dolores Chirlaque, Raul Zamora-Ros and 13 more

Abstract read
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Reply to: "Alcohol Intake and Parkinson's Symptoms Following Diagnosis".Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  7. Lifestyle medicine in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  8. Association between alcohol consumption and mortality in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Epidemiology of Parkinson's Disease: An Update.Current neurology and neuroscience reports · 2024
    Review
  17. Review
  18. The Role of Diet in Parkinson's Disease.Journal of Parkinson's disease · 2024
    Review
  19. Epigenetic associations ofFrontiers in psychiatry · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Susan PetersInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.ORCID 0000-0001-5662-1971
Valentina GalloCentre for Primary Care and Public Health, Queen Mary University of London, London, UK.ORCID 0000-0002-1268-8629
Paolo VineisSchool of Public Health, Imperial College London, London, UK.
Lefkos T MiddletonSchool of Public Health, Imperial College London, London, UK.
Lars ForsgrenDepartment of Clinical Sciences, Neurosciences, Umeå University, Umeå, Sweden.
Carlotta SacerdoteUnit of Cancer Epidemiology, Città della Salute e della Scienza University-Hospital, Turin, Italy.
Sabina SieriEpidemiology and Prevention Unit, Fondazione Istitutodi Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale dei Tumori, Milan, Italy.
Andreas KyrozisHellenic Health Foundation, Athens, Greece.
María-Dolores ChirlaqueDepartment of Epidemiology, Regional Health Council, Instituto Murciano de Investigación Biosanitaria (IMIB)-Arrixaca, Murcia, Spain.
Raul Zamora-RosUnit of Nutrition and Cancer, Epidemiology Research Program, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, Hospitalet de Llobregat, Barcelona, Spain.
Oskar HanssonClinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden.
Jesper PeterssonDepartment of Neurology, Skåne University Hospital, Lund University, Malmö, Sweden.
Verena KatzkeGerman Cancer Research Centre, Heidelberg, Germany.
Tilman KühnGerman Cancer Research Centre, Heidelberg, Germany.
Olatz MokoroaPublic Health Division of Gipuzkoa, BioDonostia Research Institute, San Sebastian, Spain.
Giovanna MasalaCancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network-Cancer Research and Prevention Institute (ISPRO), Florence, Italy.
Eva ArdanazCentrode Investigación Biomédica en Red (CIBER) in Epidemiology and Public Health, Madrid, Spain.
Salvatore PanicoDipartimento di Medicina Clinica e Chirurgia, Federico II University Naples, Naples, Italy.
Manuela M BergmannGerman Institute of Human Nutrition, Potsdam-Rehbrücke, Germany.
Timothy J KeyNuffield Department of Population Health, University of Oxford, Oxford, UK.
Elisabete WeiderpassInternational Agency for Research on Cancer, Lyon, France.
Pietro FerrariInternational Agency for Research on Cancer, Lyon, France.
Roel VermeulenInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.

Funding

British Heart FoundationCancer Research UK 14136Cancer Research UK 570/A16491Cancer Research UK C8221/A19170Cancer Research UK C864/A14136Department of HealthMedical Research Council G0401527Medical Research Council G0500300Medical Research Council G1000143Medical Research Council MC-UU_12015/1Medical Research Council MR/M012190/1Medical Research Council MR/N003284/1Wellcome Trust 205212/Z/16/ZWorld Health Organization 001
6 · The paper itself

Abstract

backgroundParkinson's disease (PD) etiology is not well understood. Reported inverse associations with smoking and coffee consumption prompted the investigation of alcohol consumption as a risk factor, for which evidence is inconclusive.

objectiveTo assess the associations between alcohol consumption and PD risk.

methodsWithin NeuroEPIC4PD, a prospective European population-based cohort, 694 incident PD cases were ascertained from 209,998 PD-free participants. Average alcohol consumption at different time points was self-reported at recruitment. Cox regression hazard ratios were estimated for alcohol consumption and PD occurrence.

resultsNo associations between baseline or lifetime total alcohol consumption and PD risk were observed. Men with moderate lifetime consumption (5-29.9 g/day) were at ~50% higher risk compared with light consumption (0.1-4.9 g/day), but no linear exposure-response trend was observed. Analyses by beverage type also revealed no associations with PD.

conclusionOur data reinforce previous findings from prospective studies showing no association between alcohol consumption and PD risk. © 2020 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.

Indexed as

Parkinson DiseaseAlcohol DrinkingCoffeeCohort StudiesHumansMaleProspective StudiesRisk FactorsCoffeealcoholEPICepidemiologyParkinsonprospective cohort

Identifiers

PMID32357270
PMCPMC7496254

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.