Evidence map›Paper›PMID 32357074›Full record

ArticleCirculation. Heart failure2020

Advanced Pulmonary and Cardiac Support of COVID-19 Patients: Emerging Recommendations From ASAIO

Keshava Rajagopal, Steven P Keller, Bindu Akkanti, Christian Bime, Pranav Loyalka, Faisal H Cheema, Joseph B Zwischenberger, Aly El Banayosy, Federico Pappalardo, Mark S Slaughter and 1 more

Open access · greenAbstract read
In one paragraph

Article in Circulation. Heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. ECMO in COVID-19 Patients: A Systematic Review and Meta-analysis.Journal of cardiothoracic and vascular anesthesia · 2022
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Pulmonary Rehabilitation in Patients with COVID-19-A Protocol for Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. [COVID-19 and mechanical circulatory support].Annales de cardiologie et d'angeiologie · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 2 countries.

Keshava RajagopalUniversity of Houston College of Medicine, TX (K.R., F.H.C.).
Steven P KellerBrigham and Women's Hospital and Harvard Medical School, Boston, MA (S.P.K.).
Bindu AkkantiUniversity of Texas-Houston, Memorial Hermann-Texas Medical Center (B.A.).
Christian BimeUniversity of Arizona College of Medicine and Banner Health, Tucson (C.B., M.J.S.).
Pranav LoyalkaHouston Heart, HCA Houston Healthcare, TX (K.R., P.L., F.H.C.).
Faisal H CheemaUniversity of Houston College of Medicine, TX (K.R., F.H.C.).
Joseph B ZwischenbergerUniversity of Kentucky College of Medicine and Medical Center, Lexington (J.B.Z.).
Aly El BanayosyIntegris Baptist Medical Center, Oklahoma City (A.E.-B.).
Federico PappalardoVita-Salute San Raffaele University, Milan, Italy (F.P.).
Mark S SlaughterUniversity of Louisville School of Medicine and Jewish Hospital, KY (M.S.S.).
Marvin J SlepianUniversity of Arizona College of Medicine and Banner Health, Tucson (C.B., M.J.S.).
Houston Methodist · USBanner Health · USBrigham and Women's Hospital · USINTEGRIS Baptist Medical Center · USJewish Hospital · USMemorial Hermann–Texas Medical Center · USUniversity of Kentucky · USVita-Salute San Raffaele University · IT

Funding

Optimizing Cardiovascular Device Thromboresistance for Eliminating AnticoagulantsU01EB012487 · NIBIB · STATE UNIVERSITY NEW YORK STONY BROOK · PI BLUESTEIN, DANNY · 2010 to 2014
$6.9M
Multiscale Modeling of Blood Flow and Platelet Mediated ThrombosisU01HL131052 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI BLUESTEIN, DANNY · 2016 to 2020
$3.6M
SELPLG as a candidate gene in Acute Respiratory Distress SyndromeK08HL141623 · NHLBI · UNIVERSITY OF ARIZONA · PI BIME, CHRISTIAN · 2018 to 2022
$863k
Functional restoration of ventriculo-arterial coupling in cardiogenic shock via dual mechanical supportK08HL143342 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KELLER, STEVEN PAUL · 2018 to 2023
$853k
NHLBI NIH HHS K08 HL141623NHLBI NIH HHS K08 HL143342NHLBI NIH HHS U01 HL131052NIBIB NIH HHS U01 EB012487
6 · The paper itself

Abstract

The severe acute respiratory syndrome-CoV-2 is an emerging viral pathogen responsible for the global coronavirus disease 2019 pandemic resulting in significant human morbidity and mortality. Based on preliminary clinical reports, hypoxic respiratory failure complicated by acute respiratory distress syndrome is the leading cause of death. Further, septic shock, late-onset cardiac dysfunction, and multiorgan system failure are also described as contributors to overall mortality. Although extracorporeal membrane oxygenation and other modalities of mechanical cardiopulmonary support are increasingly being utilized in the treatment of respiratory and circulatory failure refractory to conventional management, their role and efficacy as support modalities in the present pandemic are unclear. We review the rapidly changing epidemiology, pathophysiology, emerging therapy, and clinical outcomes of coronavirus disease 2019; and based on these data and previous experience with artificial cardiopulmonary support strategies, particularly in the setting of infectious diseases, provide consensus recommendations from American Society for Artificial Internal Organs. Of note, this is a living document, which will be updated periodically, as additional information and understanding emerges.

Indexed as

BetacoronavirusHeartLungCoronavirus InfectionsCOVID-19HumansPandemicsPneumonia, ViralSARS-CoV-2Societies, MedicalARDScoronavirusextracorporeal membrane oxygenationmechanical circulatory supportpandemicshock

Identifiers

PMID32357074
PMCPMC7304497
OpenAlexW3023645869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.