ArticleEnvironmental science & technology2020
Occurrence and Mass Loading of Synthetic Opioids, Synthetic Cathinones, and Synthetic Cannabinoids in Wastewater Treatment Plants in Four U.S. Communities.
Article in Environmental science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Current state and future perspectives on de facto population markers for normalization in wastewater-based epidemiology: A systematic literature review.The Science of the total environment · 2024Pooled it
- The rising wave of cathinone use in people attending harm reduction facilities: a French repeated cross-sectional study (2019-2023).Addiction science & clinical practice · 2026Article
- Data Hidden in Sewage: Advanced Methods for Identification and Quantification of Synthetic Cannabinoids in Urban Wastewater.Molecules (Basel, Switzerland) · 2026Review
- Ultra-high sensitive MSPE-UPLC-MS/MS method based on magnetic nanoparticles for the detection of synthetic cannabinoids in wastewater.Mikrochimica acta · 2025Article
- [Simultaneous determination of 38 indazole amides synthetic cannabinoids and 15 metabolites in wastewater by solid phase extraction-liquid chromatography-tandem mass spectrometry].Se pu = Chinese journal of chromatography · 2025Article
- Target and Nontarget Screening to Support Capacity Scaling for Substance Use Assessment through a Statewide Wastewater Surveillance Network in New York.Environmental science & technology · 2024Article
- Fluorinated-Squaramide Covalent Organic Frameworks for High-Performance and Interference-Free Extraction of Synthetic Cannabinoids.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Three years of wastewater surveillance for new psychoactive substances from 16 countries.Water research X · 2023Article
- An Evaluation of Pumping Stations for Pressure Sewers System Made from Concrete Coils, Polymer Concrete, and High-Density Polyethylene (HDPE).Materials (Basel, Switzerland) · 2023Article
- Determination of total cathinones with a single molecularly imprinted fluorescent sensor assisted by electromembrane microextraction.Mikrochimica acta · 2022Article
- "Waste Not, Want Not" - Leveraging Sewer Systems and Wastewater-Based Epidemiology for Drug Use Trends and Pharmaceutical Monitoring.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2021Article
- Isoprostanes in wastewater as biomarkers of oxidative stress during COVID-19 pandemic.Chemosphere · 2021Article
- Investigation of Biotransformation Products ofMetabolites · 2021Article
- Basketball and drugs: Wastewater-based epidemiological estimation of discharged drugs during basketball games in Kentucky.The Science of the total environment · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A few new psychoactive substances (NPS) that mimic the effects of controlled neuropsychiatric and illicit drugs have been forensically identified in the U.S. Wastewater-based epidemiology (WBE) can provide a comprehensive and more cost- and time-effective method of determining the prevalence of NPSs in communities. In this study, an analytical method capable of simultaneous determination of trace-level 40 NPS residues (synthetic opioids, synthetic cannabinoids, synthetic cathinones, piperazines, indole, and amphetamine) in wastewater was developed and validated. The developed analytical method was utilized to determine the occurrence of NPSs in four rural communities in southern Illinois. Nine NPSs (carfentanil, furanyl fentanyl, methoxyacetyl fentanyl, MAB-CHMINACA, methcathinone, 4-methyl pentedrone, 2-methyl-4'-(methylthio)-2-morpholinopropiophenone (MMMP), 1-(3-chlorophenyl) piperazine (mCPP), and 5-(2-Aminopropyl) Indole (5IT) were quantified. Methcathinone was the most frequently detected NPS (detection frequency, df = 100%) followed closely by the MMMP and mCPP (df = 91%). The mass loading of methcathinone, mCPP, and 5-IT using ammoniacal nitrogen-based population were up to 21.1 ± 1.3 mg/d/1000 people, 15.0 ± 0.5 mg/d/1000 people, and 9.75 ± 2.72 mg/d/1000 people, respectively. This is the first study to determine the occurrence of NPSs including synthetic opioids, synthetic cannabinoids, synthetic cathinones, and piperazines in the U.S. communities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.