Evidence map›Paper›PMID 32356726›Full record

ArticleeLife2020

Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation.

Ira Alexandra Iosub, Robert Willem van Nues, Stuart William McKellar, Karen Jule Nieken, Marta Marchioretto, Brandon Sy, Jai Justin Tree, Gabriella Viero, Sander Granneman

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Bacterial small regulatory RNAs.Nature reviews. Microbiology · 2026
    Review
  2. Article
  3. Distribution of prophage-encoded Pas sRNAs across pathogenicbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Advances in sRNA-mediated regulation ofFrontiers in cellular and infection microbiology · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ira Alexandra IosubCentre for Synthetic and Systems Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0002-2924-2471
Robert Willem van NuesInstitute of Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.
Stuart William McKellarCentre for Synthetic and Systems Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0003-0792-9878
Karen Jule NiekenInstitute of Cell Biology, University of Edinburgh, Edinburgh, United Kingdom.
Marta MarchiorettoInstitute of Biophysics, CNR Unit, Trento, Italy.
Brandon SySchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia.
Jai Justin TreeSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia.
Gabriella VieroInstitute of Biophysics, CNR Unit, Trento, Italy.ORCID 0000-0002-6755-285X
Sander GrannemanCentre for Synthetic and Systems Biology, University of Edinburgh, Edinburgh, United Kingdom.ORCID 0000-0003-4387-1271

Funding

Australian Medical Research Council GNT1139313Australian National Health GNT1067241Medical Research Council MR/K001744/1Medical Research Council MR/R008205/1Wellcome TrustWellcome Trust 091549Wellcome Trust 102334
6 · The paper itself

Abstract

By shaping gene expression profiles, small RNAs (sRNAs) enable bacteria to efficiently adapt to changes in their environment. To better understand how

Indexed as

Energy MetabolismGene Expression Regulation, BacterialRNA Processing, Post-Transcriptional3' Untranslated Regions5' Untranslated RegionsAdaptation, PhysiologicalDatabases, GeneticEscherichia coliEscherichia coli ProteinsHost Factor 1 ProteinModels, GeneticNucleic Acid ConformationRNA, BacterialRNA, MessengerRNA, Small UntranslatedRNA Stability3' Untranslated Regions5' Untranslated RegionsEscherichia coli ProteinsHfq protein, E coliHost Factor 1 ProteinRNA, BacterialRNA, MessengerRNA, Small Untranslatedbiochemistrychemical biologychromosomesCLASHE. coligene expressionHfqnon-coding RNApost-transcriptional regulationprotein-RNA interactionsRNA-RNA interactions

Identifiers

PMID32356726
PMCPMC7213987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.