ArticleMicrobiologyOpen2020
Effects of exercise frequency on the gut microbiota in elderly individuals.
Article in MicrobiologyOpen, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Physical activity, sedentary behavior and microbiome: A systematic review and meta-analysis.Journal of science and medicine in sport · 2024Pooled it
- Effects of exercise and physical activity on gut microbiota composition and function in older adults: a systematic review.BMC geriatrics · 2023Pooled it
- Systematic Review of the Effects of Exercise and Physical Activity on the Gut Microbiome of Older Adults.Nutrients · 2022Pooled it
- The effect of elastic-band resistance training on fecal microbiota and derived metabolites of aged individuals with possible sarcopenia.Frontiers in medicine · 2026Trial
- Article
- Population-scale characterization of the oral microbiome and associations with metabolic health.Nature communications · 2026Article
- Antibiofilm Potential and Mechanisms ofMicroorganisms · 2026Article
- Understanding the human gut microbiome: from composition to disease association.Frontiers in microbiomes · 2026Review
- The brain-gut-muscle axis: a mechanism for exercise-mediated protection in brain aging.Frontiers in aging neuroscience · 2026Review
- Exercise intensity-mediated regulation of gut epithelial cells and immune function in gut microbiota dysbiosis.Journal of translational medicine · 2025Review
- From dysbiosis to longevity: a narrative review into the gut microbiome's impact on aging.Journal of biomedical science · 2025Review
- Exerkine irisin mitigates cognitive impairment by suppressing gut-brain axis-mediated inflammation.Journal of advanced research · 2025Article
- Assessing the gut microbiota composition in older adults: connections to physical activity and healthy ageing.GeroScience · 2025Observational
- Dietary intake of live microbes mitigates the mortality risk associated with sedentary behavior in US hypertensive individuals.Scientific reports · 2025Article
- Comparative analysis of gut microbiota in free range and house fed yaks from Linzhou County.Scientific reports · 2025Article
- The role of exercise-induced short-chain fatty acids in the gut-muscle axis: implications for sarcopenia prevention and therapy.Frontiers in microbiology · 2025Review
- Exercise as a modulator of gut microbiota for improvement of sleep quality: a narrative review.Frontiers in neuroscience · 2025Review
- The gut microbiota and aging: interactions, implications, and interventions.Frontiers in aging · 2025Review
- Association of physical activity with gut microbiome among low-income black American adults in the Southern Community Cohort Study.Gut microbes reports · 2025Article
- Short sleep time has a greater impact on the gut microbiota of female.Sleep & breathing = Schlaf & Atmung · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Growing evidence has shown that exercise can affect the gut microbiota. The effects of exercise frequency on the gut microbiota in elderly individuals are still largely unknown. In the present study, samples from 897 elderly and 1,589 adult individuals (18-60 years old) from the American Gut Project were screened. Microbial diversity and composition were analyzed by QIIME2, and microbial function was predicted by PICRUSt2. The outcomes were further analyzed by STAMP. The analysis showed that the α-diversity of gut microbiota increased with increasing age, and regular exercise reshaped the alterations in microbial composition and function induced by aging. Moreover, the α-diversity of gut microbiota was higher in overweight elderly individuals than in normoweight elderly individuals, and regular exercise significantly affected the microbial composition and function in overweight elderly individuals. In conclusion, we revealed that regular exercise benefits elderly individuals, especially overweight elderly individuals, by modulating the gut microbiota.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.