Evidence map›Paper›PMID 32356523›Full record

ArticleActa crystallographica. Section F, Structural biology communications2020

Crystallographic snapshots of the EF-hand protein MCFD2 complexed with the intracellular lectin ERGIC-53 involved in glycoprotein transport.

Tadashi Satoh, Miho Nishio, Kousuke Suzuki, Maho Yagi-Utsumi, Yukiko Kamiya, Tsunehiro Mizushima, Koichi Kato

Open access · greenAbstract read
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tadashi SatohGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.ORCID 0000-0002-4493-4978
Miho NishioGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.
Kousuke SuzukiGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.
Maho Yagi-UtsumiGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.ORCID 0000-0001-8144-740X
Yukiko KamiyaGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.
Tsunehiro MizushimaGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.ORCID 0000-0002-6631-2889
Koichi KatoGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi 467-8603, Japan.ORCID 0000-0001-7187-9612
Nagoya City University · JPNational Institutes of Natural Sciences · JP

Funding

Japan Society for the Promotion of Science JP19H03361National Institutes of Natural Sciences 19-315
6 · The paper itself

Abstract

The transmembrane intracellular lectin ER-Golgi intermediate compartment protein 53 (ERGIC-53) and the soluble EF-hand multiple coagulation factor deficiency protein 2 (MCFD2) form a complex that functions as a cargo receptor, trafficking various glycoproteins between the endoplasmic reticulum (ER) and the Golgi apparatus. It has been demonstrated that the carbohydrate-recognition domain (CRD) of ERGIC-53 (ERGIC-53

Indexed as

Amino Acid SequenceCalciumCrystallography, X-RayGlycoproteinsMannose-Binding LectinsMembrane ProteinsModels, MolecularOligosaccharidesProtein BindingProtein ConformationProtein Conformation, alpha-HelicalRecombinant ProteinsVesicular Transport ProteinsCalciumGlycoproteinsLMAN1 protein, humanMannose-Binding LectinsMCFD2 protein, humanMembrane ProteinsOligosaccharidesRecombinant ProteinsVesicular Transport Proteinscargo receptorconformational polymorphismcrystal packingERGIC-53glycoprotein transportintracellular lectinMCFD2

Identifiers

PMID32356523
PMCPMC7193514
OpenAlexW3022690997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.