Evidence map›Paper›PMID 32356232›Full record

ArticleMikrochimica acta2020

A strip test for the optical determination of influenza virus H3 subtype using gold nanoparticle coated polystyrene latex microspheres.

Xiao Liu, Jifei Yang, Qingmei Li, Yinbiao Wang, Yanhong Wang, Ge Li, Jianzhou Shi, Peiyang Ding, Junqing Guo, Ruiguang Deng and 1 more

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiao LiuCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, China.
Jifei YangKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China.
Qingmei LiKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China.
Yinbiao WangSchool of Public Health, Xinxiang Medical University, Xinxiang, 453003, China.
Yanhong WangKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China.
Ge LiCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, China.
Jianzhou ShiKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China.
Peiyang DingSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Junqing GuoKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China.
Ruiguang DengKey Laboratory of Animal Immunology, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China.
Gaiping ZhangCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002, China. zhanggaip@126.com.

Funding

Earmarked Fund for Modern Agro-industry Technology Research System of China CARS-35National Key Research and Development Program of China 2016YFD0500701Special Fund for Henan Agriculture Research System S2012-06-02
6 · The paper itself

Abstract

A strip test is described for the optical determination of influenza virus H3 subtype. It utilizes gold nanoparticle (AuNP) coated polystyrene latex microspheres (PS) as the label and a sandwich format. The AuNP and PS particles were linked using monoclonal antibodies against influenza virus as the bridge. Under the optimal conditions, the visual detection limit of the AuNP-PS-based strip test was as low as 1/16 hemagglutination unit (HAU). It was 64 times higher than that of 10 nm (4 HAU) AuNP-based strip tests. Quantitative analysis showed that the detection limit of the AuNP-PS-based strip is 0.016 HAU. The AuNP-PS-based strip test showed no cross-reactivity to the other subtypes (H1, H5, H7, or H9) of influenza viruses. Graphical abstract .

Indexed as

MicrospheresAntibodies, ImmobilizedAntibodies, MonoclonalGoldImmunoassayInfluenza A virusLimit of DetectionMetal NanoparticlesPolystyrenesAntibodies, ImmobilizedAntibodies, MonoclonalGoldPolystyrenesInfluenza virusLateral flow immunoassayNanocompositePoint-of-care testVisual determination

Identifiers

PMID32356232

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.