Evidence map›Paper›PMID 32356188›Full record

ArticleArchives of virology2020

Full-genome sequences of GII.13[P21] recombinant norovirus strains from an outbreak in Changsha, China.

Zheng Huang, Dong Yao, Shan Xiao, Dong Yang, Xinhua Ou

Open access · bronzeAbstract read
In one paragraph

Article in Archives of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zheng HuangChangsha Center for Disease Control and Prevention, Beside the Liuyang River Bridge, No. 509, Wanjiali Second North Road, Changsha, Hunan, People's Republic of China.ORCID http://orcid.org/0000-0003-3606-1019
Dong YaoChangsha Center for Disease Control and Prevention, Beside the Liuyang River Bridge, No. 509, Wanjiali Second North Road, Changsha, Hunan, People's Republic of China.
Shan XiaoChangsha Center for Disease Control and Prevention, Beside the Liuyang River Bridge, No. 509, Wanjiali Second North Road, Changsha, Hunan, People's Republic of China.
Dong YangChangsha Center for Disease Control and Prevention, Beside the Liuyang River Bridge, No. 509, Wanjiali Second North Road, Changsha, Hunan, People's Republic of China.
Xinhua OuChangsha Center for Disease Control and Prevention, Beside the Liuyang River Bridge, No. 509, Wanjiali Second North Road, Changsha, Hunan, People's Republic of China. xhouteam@163.com.ORCID http://orcid.org/0000-0001-9754-7288
Hunan Provincial Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On 31 March 2019, 68 school students suffered from vomiting, diarrhea, and abdominal pain after participating in a group activity at a commercial park. In this outbreak, multiple norovirus genotypes were observed, including GII.2[P16], GII.17[P17], and GII.13[P21]. Further, we determined the full-genome sequences of two strains of GII.13[P21] recombinant noroviruses, which were 7434 nt long. Phylogenetic analysis based on open reading frames (ORFs) 1 and 2 revealed that these recombinants were related to stains of different genotypes from different countries. The full genome nucleotide sequences of the two isolates were 97.0% and 98.0% identical to those of strains from London and Thailand, respectively. Simplot analysis revealed the presence of a break point at nt 5059 in the ORF1 region. The histo-blood group antigen binding sites were conserved in both recombinant viruses. Our findings not only provide valuable genetic information about a recombinant norovirus but also contribute to our general understanding of the evolution, genetic diversity, and distribution of noroviruses.

Indexed as

Genome, ViralBase SequenceCaliciviridae InfectionsChildChinaDisease OutbreaksFemaleGastroenteritisGenotypeHumansMaleNorovirusOpen Reading FramesPhylogeny

Identifiers

PMID32356188
PMCPMC7223583
OpenAlexW3022650064

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.