Evidence map›Paper›PMID 32356159›Full record

ArticleEuropean radiology2020

Ultrasound-guided percutaneous microwave ablation for 755 benign breast lesions: a prospective multicenter study.

Qi Yang, Hang Li, Bao-Hua Chen, Guang-Zhi He, Xiu-Ping Wu, Li-Xia Wang, Han Wu, Jian-Ping Dou, Zhi-Yu Han, Jing Zhang and 3 more

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02860104 phase2 / phase3unknown statusnot on this map

Ultrasound Guided Percutaneous Microwave Ablation for Breast Lesions: A Prospective Multicenter Study

TypeinterventionalSponsorChinese PLA General HospitalRan2012 to 2018Enrolled500ConditionsNeoplasm of BreastArmsmicrowave ablation
NCT07263451 narecruitingnot on this mapstarted 2025, after this paper: background citation

Safety and Feasibility of Irreversible Electroporation for Early-stage Breast Cancer: a Prospective, Open-Label, Single-Arm, Exploratory Study

TypeinterventionalSponsorTian'an JiangRan2025 to 2026Enrolled24ConditionsBreast CancerArmsIRE by stunning pulse therapy device
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

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  13. Efficacy and safety of microwave ablation for benign breast lesions: a systematic review and meta-analysis.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Qi YangDepartment of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Hang LiDepartment of Breast Surgery, The Affiliated Hospital of Putian University, 999 Dongzhen Road, Putian City, 351100, Fujian, China.
Bao-Hua ChenDepartment of General Surgery, The No. 908 Hospital of Joint Logistics Support Force, Yingtan, China.
Guang-Zhi HeDepartment of Ultrasound, University of Chinese Academy of Sciences Shenzhen Hospital, 4253 Songbai Road, Matian Street, Guangming District, Shenzhen, Guangdong Province, China.
Xiu-Ping WuDepartment of Breast Surgery, Zhangzhou Zhengxing Hospital, 1609 North Huancheng Road, Zhangzhou, China.
Li-Xia WangDepartment of Ultrasound, Gansu Provincial Hospital, Lanzhou, 730000, China.
Han WuDepartment of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Jian-Ping DouDepartment of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Zhi-Yu HanDepartment of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Jing ZhangDepartment of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Xiao-Ling YuDepartment of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Jie YuDepartment of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China. jiemi301@163.com.
Ping LiangDepartment of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China. liangping301@hotmail.com.
Chinese PLA General Hospital · CNChinese University of Hong Kong, Shenzhen · CNGansu Provincial Hospital · CNPutian University · CN

Funding

Fostering Funds for National Distinguished Young Scholar Science Fund and the National Clinical Research Center for Geriatric Diseases of Chinese PLA General Hospital NCRCG-PLAGH-2019011the National Key R&D Program of Ministry of Science and Technology of China 2018ZX10723-204the National Scientific Foundation Committee of Beijing JQ18021the National Scientific Foundation Committee of China 81627803, 91859201 and 81871374the National Scientific Foundation Committee of China 81971625
6 · The paper itself

Abstract

objectivesTo evaluate the clinical efficacy of microwave ablation (MWA) of benign breast lesions (BBLs) and compare the learning curves of international radiologists (IRs) and surgeons.

methodsIn total, 440 patients with 755 clinicopathologically confirmed BBLs from 5 centers were prospectively enrolled from February 2014 to July 2018. Technical success, complications, volume reduction ratio (VRR), palpability, and cosmetic satisfaction after ablation were analyzed. In addition, the ablation time (AT) and energy (AE) with the number of procedures were analyzed for learning curve evaluation.

resultsThe mean maximum diameter was 1.7 ± 0.6 cm. The complete ablation rate reached 100%, including 45.8% lesions adjacent to the skin, pectoralis, or areola. After a median follow-up of 13.7 months, the 12-month VRR of all lesions was 97.9%, and that for 1.0- to 2.0-cm and ≥ 2.0-cm lesions was 98.6% and 96.9%, respectively. A total of 55.9% of BBLs became nonpalpable (palpable in 85.7% of cases before MWA) by both the clinician and patient. The cosmetic and minimally invasive satisfaction rates were good or excellent in 98.4% and 94.5% of patients, respectively. The median AT/cm

conclusionsUltrasound-guided percutaneous MWA is a valuable technique for the treatment of BBLs.

trial registrationClinicalTrials.gov (NCT02860104) KEY POINTS: • Ultrasound-guided percutaneous microwave ablation has the potential to become a valuable technique for the treatment of benign breast lesions. • A skilled interventional radiologist shows a rapid improvement in mastering the technique.

Indexed as

AdolescentAdultAgedAged, 80 and overBreast NeoplasmsFemaleHumansMicrowavesMiddle AgedProspective StudiesRadiofrequency AblationSurgery, Computer-AssistedTreatment OutcomeUltrasonography, InterventionalYoung AdultAblation techniquesBreast neoplasmsLearning curveProspective studyUltrasonography

Identifiers

PMID32356159
OpenAlexW3023070795

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.