ArticleAnnals of translational medicine2020
Skeletal growth velocity of adolescent idiopathic scoliosis: abnormal in spine but normal in lower limbs.
Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAbnormal spinal overgrowth has been identified in patients with adolescent idiopathic scoliosis (AIS), which may be attributed to a secondary change. However, growth velocity in adolescents with different maturity statuses, and the final length of the lower extremities were not investigated in patients with AIS. Here, we compared the peak height velocity (PHV) time point of the lower limbs between AIS and healthy adolescents and analyzed whether abnormal growth of the lower limbs exists in patients with AIS.
methodsFemale AIS patients with a thoracic Cobb angle of 20° to 60° were enrolled in the current study. The major Cobb angle, length of the spine (LOS), length of the lower limbs (LLL), and height of the pelvis (HOP) were measured. In addition, RatioSL was defined as LOS/LLL; RatioSP was defined as LOS/HOP; and RatioPL was defined as HOP/LLL. All patients and healthy controls were classified into three groups according to skeleton maturity status: pre-PHV, defined as Risser 0, and open triradiate cartilage (TC); during-PHV (Risser 0, and closed TC); and post-PHV (Risser ranging from 1 to 5).
resultsRatioSL and RatioSP were significantly higher in scoliosis patients at Risser ≥4 compared to healthy controls (all, P<0.05). However, RatioPL was similar between patients with AIS and healthy controls in both the Risser 0 and Risser ≥4 groups. The change in ratio from pre-PHV to post-PHV showed similar trends between patients with AIS and healthy controls; both RatioSL and RatioPL were significantly lower in the during-PHV group (all, P<0.05).
conclusionsThe final length of the lower extremities was similar between groups, while the peak growth of the lower extremities was earlier than that of pelvis and spine in both patients with AIS and healthy adolescents, indicating that lower limb growth pattern was not altered in AIS patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.