Evidence map›Paper›PMID 32355575›Full record

ArticlePeerJ2020

The association between a free medicine program and functioning in people with schizophrenia: a cross-sectional study in Liuyang, China.

Wenjie Gong, Chao Zhang, Dong Roman Xu, Shuiyuan Xiao, Yu Yu, Eric D Caine

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Wenjie GongXiangya School of Public Health, Central South University, Changsha, Hunan Province, China.
Chao ZhangXiangya School of Public Health, Central South University, Changsha, Hunan Province, China.ORCID 0000-0002-9850-7023
Dong Roman XuSun Yat-sen University Global Health Institute (SGHI), School of Public Health & Institute of State Governance, Sun Yat-sen University, Guangzhou, Guangdong Province, China.ORCID 0000-0001-7438-632X
Shuiyuan XiaoXiangya School of Public Health, Central South University, Changsha, Hunan Province, China.
Yu YuXiangya Hospital, Central South University, Changsha, Hunan Province, China.ORCID 0000-0001-7657-720X
Eric D CaineDepartment of Psychiatry, University of Rochester, Rochester, NY, USA.
Central South University · CNSun Yat-sen University · CNUniversity of Rochester · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPersons with schizophrenia frequently discontinue or avoid medications. Under a national community-based mental health program many places in China have started to provide free medications to people with severe mental health disorders in their communities. In the free medication program (FMP) in Liuyang, China, peripatetic psychiatrists prescribed and dispensed antipsychotic medications free of charge at regular intervals and places convenient for all patients through the primary health care system since 2006. Our study aims to test whether adherence to this FMP improves the functioning of people with schizophrenia.

methodsThe research was conducted in Liuyang, a rural county in central China. Data were obtained from three sources: an ad-hoc survey and the program's management system in 2013 and in-home interviews in 2014 in Liuyang. We conducted a cross-sectional propensity-score based analysis of the "dose" effect of FMP participation on their level of functioning, using medication refill adherence as a proxy for the participatory intensity in the program.

resultsOnly 50.9% of 2,332 participants came for all refills in 2012. Higher refill adherence was associated with slightly worse functional outcomes. The main reasons for refill non-adherence were "unwilling to take medication or only took medication when unwell" (23.6%), "forgot or missed the appointment" (20.6%) and "hospitalized" (20.1%).

conclusionsThe FMP program in Liuyang seemed to have successfully removed barriers in cost and access. However, better refill adherence was not associated with better functional outcomes in this study, which might have been the result of reverse causation. To improve the effectiveness of the FMP, patient-centered measures should be considered.

Indexed as

686 ProgramCommunity-based mental healthFree medication programMedication adherence

Identifiers

PMID32355575
PMCPMC7185026
OpenAlexW3018986611

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.