Evidence map›Paper›PMID 32355561›Full record

ArticleClinical & translational immunology2020

IgG

Felix Marsh-Wakefield, Thomas Ashhurst, Stephanie Trend, Helen M McGuire, Pierre Juillard, Anna Zinger, Anderson P Jones, Allan G Kermode, Simon Hawke, Georges E Grau and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical & translational immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. B cells defined by immunoglobulin isotypes.Clinical and experimental immunology · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Mass Cytometry Identifies Expansion of T-betFrontiers in immunology · 2021
    Observational
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Felix Marsh-WakefieldSchool of Medical Sciences Faculty of Medicine and Health The University of Sydney Sydney NSW Australia.ORCID https://orcid.org/0000-0002-6839-7628
Thomas AshhurstSchool of Medical Sciences Faculty of Medicine and Health The University of Sydney Sydney NSW Australia.ORCID https://orcid.org/0000-0001-7269-7773
Stephanie TrendTelethon Kids Institute University of Western Australia Perth WA Australia.
Helen M McGuireSchool of Medical Sciences Faculty of Medicine and Health The University of Sydney Sydney NSW Australia.ORCID https://orcid.org/0000-0003-2047-6543
Pierre JuillardSchool of Medical Sciences Faculty of Medicine and Health The University of Sydney Sydney NSW Australia.
Anna ZingerVascular Immunology Unit Department of Pathology The University of Sydney Sydney NSW Australia.
Anderson P JonesTelethon Kids Institute University of Western Australia Perth WA Australia.
Allan G KermodeCentre for Neuromuscular and Neurological Disorders Perron Institute for Neurological and Translational Science University of Western Australia Perth WA Australia.
Simon HawkeVascular Immunology Unit Department of Pathology The University of Sydney Sydney NSW Australia.
Georges E GrauSchool of Medical Sciences Faculty of Medicine and Health The University of Sydney Sydney NSW Australia.
Prue H HartTelethon Kids Institute University of Western Australia Perth WA Australia.ORCID https://orcid.org/0000-0001-7207-6467
Scott N ByrneSchool of Medical Sciences Faculty of Medicine and Health The University of Sydney Sydney NSW Australia.ORCID https://orcid.org/0000-0003-3029-1710
The University of Sydney · AUThe Kids Research Institute Australia · AUMurdoch University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDisease-modifying therapies (DMTs) targeting B cells are amongst the most effective for preventing multiple sclerosis (MS) progression. IgG

methodsWe designed a 31-parameter B-cell-focused mass cytometry panel to interrogate the role of peripheral blood IgG

resultsNine distinct CD20

conclusionWe have identified previously uncharacterised subsets of IgG

Indexed as

B cellsclinically isolated syndromemass cytometrymultiple sclerosisphototherapy

Identifiers

PMID32355561
PMCPMC7190396
OpenAlexW3022812835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.