ArticleMolecular psychiatry2021
Sleep complaints are associated with increased suicide risk independently of psychiatric disorders: results from a national 3-year prospective study.
Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- Insomnia During the Perinatal Period and its Association with Maternal and Infant Psychopathology: A Systematic Review and Meta-Analysis.Current psychiatry reports · 2023Pooled it
- International Expert Opinions and Recommendations on the Use of Melatonin in the Treatment of Insomnia and Circadian Sleep Disturbances in Adult Neuropsychiatric Disorders.Frontiers in psychiatry · 2021Pooled it
- Dissecting the shared genetic architecture and biological mechanisms linking sleep traits and suicide attempts: from variants to genes.Molecular psychiatry · 2026Article
- Sleeping Less Than Usual Is Associated With Greater Daily Depression and Higher Reactivity to Negative Interpersonal Events Among Suicidal Adolescents.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026Article
- Multidimensional determinants of suicide risk in emerging adults: the roles of sleep health, chronotype, exercise participation, earthquake exposure, and gender.BMC public health · 2026Article
- Multivariate Associations Between R-PAS Variables and Suicidal Ideation and Behaviors in Help-Seeking Adolescents.Brain sciences · 2026Article
- Management of Insomnia Complaints by Non-Sleep Specialist Physicians: A French DELPHI Consensus.Journal of sleep research · 2026Article
- Sleep Problems Alter Proximal Risk of Negative Self-Perceptions on Suicide Risk.Suicide & life-threatening behavior · 2026Article
- Psychotropic medication prescribing for patients with insomnia comorbid with depressive or anxiety disorders in primary healthcare facilities in Beijing.BJPsych open · 2026Article
- Joint effects of sleep duration and sleep difficulty on suicidal ideation: evidence from NHANES 2005-2018.BMC psychiatry · 2026Article
- Novel insights into gut microbiota alterations in major depressive disorder with suicidal ideation: a metagenomic analysis.Frontiers in microbiology · 2026Article
- Napping during major depressive episodes identifies a distinct hypersomnolence phenotype.Sleep advances : a journal of the Sleep Research Society · 2026Article
- A large-scale study of chronic sleep disorders in psychiatric inpatients: Prevalence, hospitalization burden, restraint use, and comorbidities.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Sleep characteristics and non-suicidal self-injury: unveiling the association in depressed adolescents.BMC psychiatry · 2025Article
- Prediction of suicidal ideation and depression in the general population with subthreshold insomnia using machine learning models.BMC psychiatry · 2025Article
- The impact of childhood emotional maltreatment on adolescent insomnia: a chained mediation model.BMC psychology · 2025Article
- Nightmares Fluctuate Across the Menstrual Cycle and May be More Pronounced in Women With Premenstrual Syndrome.Brain and behavior · 2025Article
- Differential directional effects between insomnia symptoms and suicidal ideation across trait depression levels: a cross-lagged network analysis among Chinese medical undergraduates.Frontiers in psychiatry · 2025Article
- Omics Approaches to Investigate the Pathogenesis of Suicide.Biological psychiatry · 2024Review
- Influences of sleep, cortisol reactivity, and risk/reward-based decision-making on suicide.Journal of behavior therapy and experimental psychiatry · 2024Article
Corrections and comments
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Authors and funding
9 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prior research suggests that sleep disturbances are associated with increased risk of suicide. However, sleep disturbances are associated with a wide range of psychiatric disorders, and it is unknown whether this association is independent of psychopathology. In a large nationally representative prospective survey, the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), we used structural equation modeling to examine the shared and specific effects of three sleep complaints (i.e., trouble falling asleep, early morning awakening, and hypersomnia) on the 3-year occurrence of attempting suicide. Because psychiatric disorders increase the risk of suicide attempt almost exclusively through a general psychopathology factor representing their shared effect, covariates included that factor, prior history of suicide attempt, and a wide range of sociodemographic and clinical characteristics. The 3-year prevalence rate of suicide attempt was 0.6% (n = 241). Compared with participants who did not attempt suicide between the two waves, those who did reported significantly more frequently having trouble falling asleep (44.6% vs. 16.6%), early morning awakening (38.9% vs. 12.7%), and hypersomnia (35.0% vs. 10.7%). Following adjustments, effects of sleep complaints on this risk were significant and exerted almost exclusively through a general sleep complaints factor representing the shared effect across all sleep complaints. There were no residual associations of any individual sleep complaint with attempting suicide above that association. Sleep complaints are associated with an increased risk of attempting suicide independently of psychopathology, and should be included in suicide risk assessments as these symptoms may provide targets for reducing the risks of suicidal behaviors.
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