Evidence map›Paper›PMID 32355333›Full record

ArticleMolecular psychiatry2021

Large-scale network dynamics in neural response to emotionally negative stimuli linked to serotonin 1A binding in major depressive disorder.

Noam Schneck, Tao Tu, Harry Rubin Falcone, Jeffrey M Miller, Francesca Zanderigo, M Elizabeth Sublette, Maria A Oquendo, Barbara Stanley, Ainsley Burke, Kevin Ochsner and 2 more

Open access · greenAbstract read
In one paragraph

Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. The Complex Role of Serotonin-Dopamine-Glutamate Receptors in Major Depression.Advances in experimental medicine and biology · 2026
    Review
  5. Review
  6. Article
  7. PET-MRI Applications and Future Prospects in Psychiatry.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Noam SchneckDepartment of Psychiatry, Columbia University, New York, NY, USA. schneck@nyspi.columbia.edu.ORCID http://orcid.org/0000-0003-4522-4895
Tao TuDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.
Harry Rubin FalconeDivision of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, USA.
Jeffrey M MillerDepartment of Psychiatry, Columbia University, New York, NY, USA.
Francesca ZanderigoDepartment of Psychiatry, Columbia University, New York, NY, USA.
M Elizabeth SubletteDepartment of Psychiatry, Columbia University, New York, NY, USA.
Maria A OquendoDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-3139-4420
Barbara StanleyDepartment of Psychiatry, Columbia University, New York, NY, USA.
Ainsley BurkeDepartment of Psychiatry, Columbia University, New York, NY, USA.
Kevin OchsnerDepartment of Psychology, Columbia University, New York, NY, USA.
Paul SajdaDepartment of Biomedical Engineering, Columbia University, New York, NY, USA.ORCID http://orcid.org/0000-0002-9738-1342
J John MannDepartment of Psychiatry, Columbia University, New York, NY, USA.ORCID http://orcid.org/0000-0002-0265-6586
New York Psychoanalytic Society and Institute · USColumbia University · USUniversity of Pennsylvania · US

Funding

Suicidal Behavior: Aggression Subtypes, Childhood Adversity and Stress ResponseP50MH090964 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HEN, RENE · 2013 to 2022
$23.6M
Predicting complicated grief from grief processingK23MH114021 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI SCHNECK, NOAM · 2018 to 2023
$1.1M
NIMH NIH HHS P50 MH090964
6 · The paper itself

Abstract

Serotonergic dysfunction is implicated in major depressive disorder (MDD), but the mechanisms of this relationship remain elusive. Serotonin 1A (5-HT

Indexed as

Major Depressive DisorderSerotoninBrainHumansMagnetic Resonance ImagingPositron-Emission TomographyReceptor, Serotonin, 5-HT1AReceptor, Serotonin, 5-HT1ASerotonin

Identifiers

PMID32355333
PMCPMC7606327
OpenAlexW3022648443

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.