ArticleScientific reports2020
Different histopathologic profiles and outcomes between sun-exposed BCC and non-sun-exposed BCC.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Proportion of Japanese Patients with Multiple Basal Cell Carcinomas: The Effectiveness of Screening.Journal of plastic and reconstructive surgery · 2025Article
- Giant basal cell carcinoma in a non-sun exposed area with four years follow-up: a case report.The Pan African medical journal · 2024Article
- The Importance of Basal Cell Carcinoma Risk Stratification and Potential Future Pathways.JMIR dermatology · 2023Article
- Recurrent cutaneous basal cell carcinoma after surgical excision: A retrospective clinicopathological study.Annals of medicine and surgery (2012) · 2022Article
- Adequacy of surgical margins, re-excision, and evaluation of factors associated with recurrence: a retrospective study of 769 basal cell carcinomas.Anais brasileiros de dermatologiaArticle
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Authors and funding
4 authors.
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Abstract
Asian population is a low-risk group for basal cell carcinoma (BCC) and there is little data available in this setting. Sun-exposed BCC (SEBCC) may possess a different pathogenic mechanism from non-sun-exposed BCC (NSEBCC). To compare the histopathological profiles and outcomes between SEBCC and NSEBCC, and to assess the risk factors for tumor recurrences. Retrospective cohort study on 372 patients with pathologically diagnosed BCC from January 1, 1990 to August 31, 2017. Data were derived from a single medical center in Taiwan. SEBCC presented with higher Clark level and more high-risk factors for recurrence than NSEBCC. Nodular, micronodular, infiltrating/mixed infiltrating, basosquamous, and adenoid types were predominant in SEBCC, as superficial type in NSEBCC. Risk factors for recurrence included infiltrating/mixed-infiltrating subtypes and synchronous basosquamous cell carcinoma. No recurrence events were observed in NSEBCC. Our study showed an acceptable recurrence rate (4.2%) of the whole population after excision even under a smaller surgical margin width than suggested by current guidelines. SEBCC had a higher recurrence rate with a significantly different tumor characteristic from NSEBCC and a greater tumor depth than NSEBCC. A wider surgical margin in SEBCC than NSEBCC is suggested.
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