Evidence map›Paper›PMID 32355163›Full record

ArticleSpinal cord series and cases2020

Ambulatory urodynamic monitoring assessment of dorsal genital nerve stimulation for suppression of involuntary detrusor contractions following spinal cord injury: a pilot study.

Sean P Doherty, Anne Vanhoestenberghe, Lynsey D Duffell, Rizwan Hamid, Sarah L Knight

2 registry-linked trialsOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Spinal cord series and cases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05502614 naunknown statusnot on this mapstarted 2023, after this paper: background citation

NEUROMOD UCon: Pilot Study of Dorsal Genital Nerve Stimulation for Management of Bladder Overactivity Following Spinal Cord Injury

TypeinterventionalSponsorUniversity College, LondonRan2023 to 2024Enrolled10ConditionsSpinal Cord Injuries, Neurogenic Bladder, Neurogenic Detrusor Overactivity, Neurogenic Bladder DysfunctionArmsNeuromodulation
NCT05504200 nacompletednot on this mapstarted 2022, after this paper: background citation

Promoting Restoration of Function of Co-ordinated Bladder Storage and Voiding Following Spinal Cord Injury by Combination of Transcutaneous Spinal Cord Stimulation and Bladder & Pelvic Floor Muscle Training Training

TypeinterventionalSponsorRNOH RICRan2022 to 2023Enrolled15ConditionsSpinal Cord InjuriesArmsBladder and Pelvic Floor Muscle Training
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sean P DohertyAspire Centre for Rehabilitation Engineering and Assistive Technology, University College London, London, UK. sean.doherty.15@ucl.ac.uk.ORCID http://orcid.org/0000-0003-1665-9726
Anne VanhoestenbergheAspire Centre for Rehabilitation Engineering and Assistive Technology, University College London, London, UK.
Lynsey D DuffellAspire Centre for Rehabilitation Engineering and Assistive Technology, University College London, London, UK.
Rizwan HamidLondon Spinal Cord Injury Centre, Royal National Orthopaedic Hospital, London, UK.
Sarah L KnightLondon Spinal Cord Injury Centre, Royal National Orthopaedic Hospital, London, UK.
Royal National Orthopaedic Hospital · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designA prospective interventional pilot study using within-individual comparisons.

objectivesTo assess the effect of dorsal genital nerve stimulation (DGNS) on urine-storage parameters in participants with spinal cord injury (SCI) and neurogenic detrusor overactivity (NDO) during natural bladder filling.

settingThe London Spinal Cord Injuries Centre at the Royal National Orthopaedic Hospital, Stanmore, UK.

methodsAmbulatory urodynamic monitoring (AUM) was carried out with and without DGNS, before and after a week of using DGNS at home. DGNS was applied on-demand by four participants with bladder sensation, and both continuously and intermittently by one participant with absent sensation. A Wilcoxon sign-rank test was used to test paired results of changes within an AUM session.

resultsUrodynamic outcomes were improved using DGNS. Bladder capacity was increased from 244 ± 59 to 346 ± 61 ml (p = 0.0078), a mean change of 46 ± 25%. Maximum detrusor pressure was decreased from 58 ± 18 to 47 ± 18 cmH

conclusionsDGNS may be applied on-demand, intermittently or continuously, to increase bladder capacity, decrease storage pressures and provide extra time. Improvements were made in addition to existing antimuscarinic medication regimes.

Indexed as

UrodynamicsAdultAgedElectric Stimulation TherapyFemaleHumansMaleMiddle AgedPilot ProjectsProspective StudiesPudendal NerveSpinal Cord InjuriesTreatment Outcome

Identifiers

PMID32355163
PMCPMC7192939
OpenAlexW3022579602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.