Evidence map›Paper›PMID 32354997›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

The SrrAB two-component system regulates

Nitija Tiwari, Marisa López-Redondo, Laura Miguel-Romero, Katarina Kulhankova, Michael P Cahill, Phuong M Tran, Kyle J Kinney, Samuel H Kilgore, Hassan Al-Tameemi, Christine A Herfst and 8 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
1.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Journal of bacteriology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Activation of themBio · 2025
    Article
  10. Cell surface (Amsterdam, Netherlands) · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. First whole genome sequencing ofOpen veterinary journal · 2024
    Article
  15. Article
  16. Mutations in thebioRxiv : the preprint server for biology · 2024
    Article
  17. Article
  18. Pathogens and global health · 2024
    Review
  19. Crosstalk involving two-component systems inJournal of bacteriology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 3 countries.

Nitija TiwariDepartment of Biochemistry, University of Iowa, Iowa City, IA 52242.ORCID 0000-0001-5327-672X
Marisa López-RedondoInstituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas (IBV-CSIC), 46010 Valencia, Spain.
Laura Miguel-RomeroInstituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas (IBV-CSIC), 46010 Valencia, Spain.
Katarina KulhankovaDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242.ORCID 0000-0001-7189-2323
Michael P CahillDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242.
Phuong M TranDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242.ORCID 0000-0001-7917-7025
Kyle J KinneyDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242.ORCID 0000-0002-1029-3279
Samuel H KilgoreDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242.
Hassan Al-TameemiDepartment of Biochemistry and Microbiology, Rutgers University, New Brunswick, NJ 08901-8525.
Christine A HerfstDepartment of Microbiology and Immunology, Western University, London, ON N6A 5C1, Canada.
Stephen W TuffsDepartment of Microbiology and Immunology, Western University, London, ON N6A 5C1, Canada.ORCID 0000-0002-2874-7822
John R KirbyDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI 53226.
Jeffery M BoydDepartment of Biochemistry and Microbiology, Rutgers University, New Brunswick, NJ 08901-8525.ORCID 0000-0001-7721-3926
John K McCormickDepartment of Microbiology and Immunology, Western University, London, ON N6A 5C1, Canada.ORCID 0000-0003-3742-7289
Wilmara Salgado-PabónDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242.
Alberto MarinaInstituto de Biomedicina de Valencia, Consejo Superior de Investigaciones Científicas (IBV-CSIC), 46010 Valencia, Spain.ORCID 0000-0002-1334-5273
Patrick M SchlievertDepartment of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242.
Ernesto J FuentesDepartment of Biochemistry, University of Iowa, Iowa City, IA 52242; ernesto-fuentes@uiowa.edu.
University of Iowa · USConsejo Superior de Investigaciones Científicas · ESWestern University · CARutgers, The State University of New Jersey · USMedical College of Wisconsin · US

Funding

Enterotoxin-Mediated Development of Staphylococcus aureus Infective EndocarditisR01AI134692 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI SALGADO PABON, WILMARA · 2018 to 2023
$3.0M
Mechanisms of cellular respiration-dependent cell lysis and its impact on biofilm formation and disassembly in Staphylococcus aureus.R01AI139100 · NIAID · RUTGERS, THE STATE UNIV OF N.J. · PI BOYD, JEFF M · 2018 to 2022
$1.9M
PAS domain and redox regulation of the S. aureus SrrB sensor histidine kinaseR21AI135305 · NIAID · UNIVERSITY OF IOWA · PI FUENTES, ERNESTO JORGE · 2018 to 2019
$417k
CIHR PJT-166050NIAID NIH HHS R01 AI134692NIAID NIH HHS R01 AI139100NIAID NIH HHS R21 AI135305
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBacterial ProteinsBacterial ToxinsBase SequenceBiofilmsCatalytic DomainCysteineDisease Models, AnimalEndocarditisEnterotoxinsFemaleGene Expression Regulation, BacterialHistidine KinaseMaleModels, MolecularMutationBacterial ProteinsBacterial ToxinsCysteineenterotoxin F, StaphylococcalEnterotoxinsHistidine KinaseRepressor ProteinsSrrA protein, Staphyolococcus aureusSrrB protein, Staphyolococcus aureusSuperantigenscysteine disulfide bondsensor histidine kinaseSrrAB two-component systemStaphylococcus aureus

Identifiers

PMID32354997
PMCPMC7245129
OpenAlexW3022690159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.