Evidence map›Paper›PMID 32354949›Full record

ArticleIn vivo (Athens, Greece)

Efficacy of Nivolumab Plus Ipilimumab in a Patient With Renal Cell Carcinoma Concomitant With Cardiac Metastasis: A Case Report.

Suguru Shirotake, Yuta Umezawa, Takashi Okabe, G O Kaneko, Kent Kanao, Koshiro Nishimoto, Masafumi Oyama

Open access · diamondAbstract readCase Reports
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Suguru ShirotakeDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Hidaka, Japan ss6001@5931.saitama-med.ac.jp.
Yuta UmezawaDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Hidaka, Japan.
Takashi OkabeDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Hidaka, Japan.
G O KanekoDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Hidaka, Japan.
Kent KanaoDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Hidaka, Japan.
Koshiro NishimotoDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Hidaka, Japan.
Masafumi OyamaDepartment of Uro-Oncology, Saitama Medical University International Medical Center, Hidaka, Japan.
Saitama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimPatients with metastatic renal cell carcinoma (RCC) with cardiac metastasis have had poor outcomes in the era of molecular targeted therapy. There are few reported outcomes for patients with cardiac metastasis of RCC treated with immune checkpoint inhibitors (ICIs). CASE REPORT: A 32-year-old female presented with metastatic RCC (unclassified type) with contralateral renal and cardiac metastases, as well as renal hilar lymph node metastases (cT4N2M1). An

conclusionThis successful case suggests that ICIs might provide a better outcome even for patients with cardiac metastasis of RCC, and that FDG-PET/CT scan might be useful for therapeutic assessment, as well as diagnosis.

Indexed as

AdultAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Renal CellFemaleFluorodeoxyglucose F18Heart NeoplasmsHumansImmunohistochemistryIpilimumabNeoplasm StagingNivolumabPositron Emission Tomography Computed TomographyTomography, X-Ray ComputedTreatment OutcomeFluorodeoxyglucose F18IpilimumabNivolumabcardiac metastasisFDG-PET/CT scannivolumab plus ipilimumabRenal cell carcinoma

Identifiers

PMID32354949
PMCPMC7279812
OpenAlexW3021017030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.