Evidence map›Paper›PMID 32354948›Full record

ArticleIn vivo (Athens, Greece)

The Impact of Intraoperative Blood Loss on the Survival of Patients With Stage II/III Pancreatic Cancer.

Hiroshi Tamagawa, Toru Aoyama, Naoto Yamamoto, Mariko Kamiya, Masaaki Murakawa, Yosuke Atsumi, Masakatsu Numata, Keisuke Kazama, Kentaro Hara, Norio Yukawa and 3 more

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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  6. A practical recurrence risk model based on Lasso-Cox regression for gastric cancer.Journal of cancer research and clinical oncology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Hiroshi TamagawaDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan rinta77-nosuke@amber.plala.or.jp t-aoyama@lilac.plala.or.jp.
Toru AoyamaDepartment of Surgery, Yokohama City University, Yokohama, Japan rinta77-nosuke@amber.plala.or.jp t-aoyama@lilac.plala.or.jp.
Naoto YamamotoDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Mariko KamiyaDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Masaaki MurakawaDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Yosuke AtsumiDepartment of Surgery, Yokohama City University, Yokohama, Japan.
Masakatsu NumataDepartment of Surgery, Yokohama City University, Yokohama, Japan.
Keisuke KazamaDepartment of Surgery, Yokohama City University, Yokohama, Japan.
Kentaro HaraDepartment of Surgery, Yokohama City University, Yokohama, Japan.
Norio YukawaDepartment of Surgery, Yokohama City University, Yokohama, Japan.
Yasushi RinoDepartment of Surgery, Yokohama City University, Yokohama, Japan.
Munetaka MasudaDepartment of Surgery, Yokohama City University, Yokohama, Japan.
Soichiro MorinagaDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Yokohama City University · JPKanagawa Prefectural Hospital Organization · JPKanagawa Cancer Center

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPancreatic cancer is a fatal disease with a poor prognosis. Pancreatic cancer is often unresectable at the time of diagnosis, so the analysis of risk factors in patients with indications for surgery is important. We investigated the impact of intraoperative blood loss (IBL) on survival and recurrence in patients with stage II/III pancreatic cancer after curative surgery. PATIENTS AND

methodsThis study included 76 patients who underwent curative surgery for stage II/III pancreatic cancer between 2007 and 2012. The risk factors for overall (OS) and recurrence-free (RFS) survival were identified.

resultsIBL of 1,000 ml was considered to be the optimal cut-off value for classification based on a receiver operating characteristic (ROC) curve analysis. The OS rates at 5 years after surgery in the groups with low and high IBL were 36.6% and 11.4%, respectively, which was a statistically significant difference (p=0.003). The RFS rates at 1 year after surgery were 49.8% and 24.6%, respectively, which was a significant difference (p=0.045). A multivariate analysis demonstrated that IBL was a significant independent risk factor for OS.

conclusionIBL is an independent prognostic factor after curative resection of stage II/III pancreatic cancer. The reduction of bleeding during surgery is necessary to improve the results of pancreatic cancer surgery.

Indexed as

AdultAgedAged, 80 and overBlood Loss, SurgicalFemaleFollow-Up StudiesHumansIntraoperative PeriodMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingPancreatic NeoplasmsPrognosisProportional Hazards ModelsRisk FactorsIntraoperative blood lossPancreatic cancerrecurrencesurvival

Identifiers

PMID32354948
PMCPMC7279845
OpenAlexW3021013495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.