Evidence map›Paper›PMID 32354944›Full record

ArticleIn vivo (Athens, Greece)

Cervical Pathology Following HPV Vaccination in Greece: A 10-year HeCPA Observational Cohort Study.

Evangelos Paraskevaidis, Antonios Athanasiou, Maria Paraskevaidi, Evripidis Bilirakis, Georgios Galazios, Emmanuel Kontomanolis, Konstantinos Dinas, Aristotelis Loufopoulos, Maria Nasioutziki, Ioannis Kalogiannidis and 16 more

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 6 institutions in 1 country.

Evangelos ParaskevaidisDepartment of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece vangelispar@hotmail.com.
Antonios AthanasiouInstitute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, U.K.
Maria ParaskevaidiInstitute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, U.K.
Evripidis BilirakisDepartment of Obstetrics and Gynaecology, IASO Hospital, Athens, Greece.
Georgios GalaziosDepartment of Obstetrics and Gynaecology, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Emmanuel KontomanolisDepartment of Obstetrics and Gynaecology, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Konstantinos DinasSecond Department of Obstetrics and Gynaecology, University of Thessaloniki, Thessaloniki, Greece.
Aristotelis LoufopoulosSecond Department of Obstetrics and Gynaecology, University of Thessaloniki, Thessaloniki, Greece.
Maria NasioutzikiSecond Department of Obstetrics and Gynaecology, University of Thessaloniki, Thessaloniki, Greece.
Ioannis KalogiannidisThird Department of Obstetrics and Gynaecology, University of Thessaloniki, Thessaloniki, Greece.
Apostolos AthanasiadisThird Department of Obstetrics and Gynaecology, University of Thessaloniki, Thessaloniki, Greece.
Alexios PapanikolaouSecond Department of Obstetrics and Gynaecology, University of Thessaloniki, Thessaloniki, Greece.
Anastasia VatopoulouFirst Department of Obstetrics and Gynaecology, University of Thessaloniki, Thessaloniki, Greece.
Gregorios GrimbizisFirst Department of Obstetrics and Gynaecology, University of Thessaloniki, Thessaloniki, Greece.
Dimitrios TsolakidisFirst Department of Obstetrics and Gynaecology, University of Thessaloniki, Thessaloniki, Greece.
Alexandros DaponteDepartment of Obstetrics and Gynaecology, University Hospital of Larissa, Larissa, Greece.
George ValasoulisDepartment of Obstetrics and Gynaecology, University Hospital of Larissa, Larissa, Greece.
Stella GritzeliDepartment of Obstetrics and Gynaecology, General Hospital of Larissa, Larissa, Greece.
Georgios MichailDepartment of Obstetrics and Gynaecology, University Hospital of Patras, Patras, Greece.
Georgios AdonakisDepartment of Obstetrics and Gynaecology, University Hospital of Patras, Patras, Greece.
Minas PaschopoulosDepartment of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece.
Orestis TsonisDepartment of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece.
Maria-Eugenia AnaforidouDepartment of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece.
Anna BatistatouDepartment of Pathology, University Hospital of Ioannina, Ioannina, Greece.
Maria KyrgiouInstitute of Reproductive and Developmental Biology, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, U.K.
HeCPA (Hellenic Cervical Pathology Academic) Group
Aristotle University of Thessaloniki · GRUniversity Hospital of Ioannina · GRUniversity Hospital of Larissa · GRGeneral University Hospital of Patras · GRUniversity Hospital of Alexandroupolis · GRIASO General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Greece the population-level impact of HPV vaccination is unknown due to lack of official registries. This study presents in a pragmatic frame the comparison of cervical pathology data between HPV-vaccinated and unvaccinated women referred for colposcopy. PATIENTS AND

methodsThis is an observational prospective cohort study performed in 7 academic Obstetrics and Gynaecology Departments across Greece between 2009-2019. Cases were women that had completed HPV vaccination before coitarche and were referred for colposcopy due to abnormal cytology. For each vaccinated woman an unvaccinated matched control was selected.

resultsA total of 849 women who had been vaccinated before coitarche and 849 unvaccinated controls were recruited. The combination of cytological, colposcopic and molecular findings necessitated treatment in only a single case among vaccinated (0.1%) and in 8.4% among unvaccinated.

conclusionHPV vaccination at a proper age can markedly reduce development of severe cervical precancers and consequently the need for treatment, as well as their long-term related obstetrical morbidity.

Indexed as

AdultCervix UteriCohort StudiesColposcopyCytodiagnosisFemaleGreeceHumansPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesPublic Health SurveillanceUterine Cervical NeoplasmsVaccinationPapillomavirus VaccinesHPVvaccinationvaccine

Identifiers

PMID32354944
PMCPMC7279786
OpenAlexW3021455422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.