Evidence map›Paper›PMID 32354931›Full record

ArticleIn vivo (Athens, Greece)

A Simple Implement for Assessing the Survival of Elderly Patients With Melanoma Irradiated for Cerebral Metastases.

Trang Nguyen, Stefan Janssen, Steven E Schild, Dirk Rades

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Trang NguyenDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Stefan JanssenDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany.
Steven E SchildDepartment of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, U.S.A.
Dirk RadesDepartment of Radiation Oncology, University of Lübeck, Lübeck, Germany rades.dirk@gmx.net.
University of Lübeck · DEMayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimSecondary brain lesions occur commonly in patients with advanced melanoma. Despite increasing use of local therapies, many elderly patients qualify for whole-brain radiotherapy (WBRT). For these patients, a survival score was created. PATIENTS AND

methodsSeven characteristics were retrospectively investigated in 35 elderly (≥65 years) patients with melanoma, namely WBRT regimen, age, gender, Karnofsky performance score (KPS), number of brain lesions, non-cerebral metastases and interval from melanoma diagnosis to WBRT.

resultsAge ≤71 years (p=0.044) and KPS ≥80% (p=0.005) were significantly associated with more favorable survival. Based on these characteristics, patients received 0 (n=13), 1 (n=12) or 2 points (n=10). Two prognostic groups were designed, 0 or 1 point vs. 2 points, with actuarial 6-month survival rates of 12% and 48%, respectively (p=0.002).

conclusionThis simple implement allows quick estimation of the survival of elderly patients receiving WBRT for cerebral metastases from melanoma.

Indexed as

Cranial IrradiationAgedAged, 80 and overBrain NeoplasmsFemaleHumansKaplan-Meier EstimateMaleMelanomaPrognosisRadiotherapy DosageTreatment Outcomecerebral metastaseselderly patientsMelanomaprognostic toolsurvivalwhole-brain radiotherapy

Identifiers

PMID32354931
PMCPMC7279822
OpenAlexW3021063347

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.