Evidence map›Paper›PMID 32354901›Full record

ArticleIn vivo (Athens, Greece)

Does Age Matter? Estimating Risks of Locoregional Recurrence After Breast-conservative Surgery.

Gianluca Vanni, Marco Materazzo, Marco Pellicciaro, Ljuba Morando, Ilaria Portarena, Lucia Anemona, Maria Rolando D'Angelillo, Rosaria Barbarino, Agostino Chiaravalloti, Rosaria Meucci and 6 more

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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  6. Biological Activities of Molecules Derived fromLife (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Gianluca VanniBreast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
Marco MaterazzoBreast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy mrcmaterazzo@gmail.com.
Marco PellicciaroBreast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
Ljuba MorandoBreast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
Ilaria PortarenaDepartment of Oncology, Policlinico Tor Vergata University, Rome, Italy.
Lucia AnemonaAnatomic Pathology, Department of Experimental Medicine, Policlinico Tor Vergata University, Rome, Italy.
Maria Rolando D'AngelilloRadiotherapy Unit, Department of Oncology and Hematology, Policlinico Tor Vergata University, Rome, Italy.
Rosaria BarbarinoRadiotherapy Unit, Department of Oncology and Hematology, Policlinico Tor Vergata University, Rome, Italy.
Agostino ChiaravallotiDepartment of Biomedicine and Prevention, Policlinico Tor Vergata University, Rome, Italy.
Rosaria MeucciBreast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
Tommaso PerrettaDepartment of Diagnostic Imaging and Interventional Radiology, Molecular Imaging and Radiotherapy, Policlinico Tor Vergata University, Rome, Italy.
Camilla DeianaBreast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
Paolo OrsariaDepartment of Breast Surgery, University Campus Bio-Medico, Rome, Italy.
Jonathan CaspiBreast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
Chiara Adriana PistoleseDepartment of Diagnostic Imaging and Interventional Radiology, Molecular Imaging and Radiotherapy, Policlinico Tor Vergata University, Rome, Italy.
Oreste Claudio BuonomoBreast Unit - Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
Policlinico Tor Vergata · ITIstituto Neurologico Mediterraneo · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimIn 2016, in the United States, more than 50% of breast cancer (BC) cases were diagnosed in patients older than 60 years of age. Our study aimed to estimate the risk of locoregional recurrence (LR) in patients who underwent breast-conservative treatment (BCT), according to age. PATIENTS AND

methodsThis retrospective monocentric study analyzed 613 cases of patients who underwent BCT between 2003 and 2014. Patients were divided into groups according to age: Under70 (under 70 years old) and Over70 (above 70 years old). Margins width, histology results, prognostic and predictive factors were compared. Subgroup analysis was performed for patients who experienced LR.

resultsLR Incidence among Under70 and Over70 was 5.4% and 1.7%, respectively (p<0.01). Group Over70 is characterized by larger tumors and a lower Ki67 index (p<0.01).

conclusionOperation time reduction, better aesthetic results and reduced LR risk support BCT. The Over70 group exhibited better outcomes in terms of LR despite larger tumor dimensions.

Indexed as

AgedAged, 80 and overBiomarkers, TumorBreast NeoplasmsCase-Control StudiesFemaleHumansMastectomy, SegmentalMiddle AgedNeoplasm Recurrence, LocalPostoperative CarePrognosisReceptors, EstrogenRetrospective StudiesRiskBiomarkers, TumorReceptors, Estrogenbreast cancerBreast cancerbreast-conservative treatmentelderlytailored treatment

Identifiers

PMID32354901
PMCPMC7279857
OpenAlexW3022234010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.