ArticleDrug and alcohol dependence2020
Characterizing profiles of polysubstance use among high school students in Baltimore, Maryland: A latent class analysis.
Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using Latent Class Analysis to Examine Polysubstance Use Patterns in Adolescents Aged 10-18: A Systematic Review.Addictive behaviors · 2025Pooled it
- Trends in Associations Between Substance Use and Suicidality and Patterns of Current Substance Use in U.S. Adolescents: A Repeated Cross-Sectional Study.American journal of preventive medicine · 2026Article
- Grade-Level Differences in the Profiles of Substance Use and Behavioral Health Problems: A Multi-Group Latent Class Analysis.International journal of environmental research and public health · 2024Article
- Polysubstance Use among Maryland High School Students: Variations across County-Level School Districts.International journal of environmental research and public health · 2024Article
- E-cigarettes may serve as a gateway to conventional cigarettes and other addictive drugs.Advances in drug and alcohol research · 2023Review
- The latent class structure of substance use in US adults 50 years and older.International journal of geriatric psychiatry · 2021Article
- Adolescent Anabolic-Androgenic Steroid Use in Association with Other Drug Use, Injection Drug Use, and Team Sport Participation.Journal of child & adolescent substance abuse · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundAdolescent drug use has long term health consequences, like substance use disorders and psychiatric illnesses. Proximal health risks, especially for overdose, are amplified when multiple substances are combined. Existing literature on polysubstance use among adolescents has largely focused on alcohol, tobacco, and marijuana, but has largely excluded other drugs like opioids. Understanding how adolescents combine illicit drugs is essential for intervening to prevent poor health outcomes.
methodsWe aimed to explore patterns of lifetime polysubstance use among adolescents in Baltimore City. We used data on 9th-12th graders recruited to participate in the 2017 local Baltimore Youth Risk Behavior Survey who reported any lifetime drug use (n = 387; 60 % female, 77 % non-Hispanic Black). We then conducted a latent class analysis using 10 indicators of lifetime drug and alcohol use. After selecting the class model, we tested for associations between the class profiles and race, sex, school grade, and lifetime injection drug use.
resultsWe identified three profiles of lifetime polysubstance use in our sample: alcohol and marijuana (68.6 % of sample), polysubstance (22.0 %), and alcohol/pain medication/inhalant use (9.4 %). Members of the polysubstance use class were more likely to be male and to report injection drug use.
conclusionsUnderstanding broader patterns of drug use beyond alcohol, tobacco and marijuana among adolescents is a crucial step towards preventing adverse drug and health-related outcomes later in life. More research is needed to characterize the full health impact of youth polysubstance use patterns and related risk behaviors like injection drug use.
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