Evidence map›Paper›PMID 32354364›Full record

Observational studyBMC palliative care2020

Severe pain at the end of life: a population-level observational study.

A Meaghen Hagarty, Shirley H Bush, Robert Talarico, Julie Lapenskie, Peter Tanuseputro

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC palliative care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

A Meaghen HagartyDepartment of Medicine, Division of Palliative Care, University of Ottawa, Ottawa, Ontario, Canada.
Shirley H BushDepartment of Medicine, Division of Palliative Care, University of Ottawa, Ottawa, Ontario, Canada.
Robert TalaricoOttawa Hospital Research Institute, 1053 Carling Avenue, Ottawa, ON, K1Y4E9, Canada.
Julie LapenskieBruyère Research Institute, Ottawa, Ontario, Canada.
Peter TanuseputroDepartment of Medicine, Division of Palliative Care, University of Ottawa, Ottawa, Ontario, Canada. ptanuseputro@ohri.ca.
Bruyère · CAInstitute of Population and Public Health · CAOttawa Hospital · CAUniversity of Ottawa · CA

Funding

Bruyère Centre for Individualized Health N/AOntario Ministry of Health and Long-Term Care 255
6 · The paper itself

Abstract

backgroundPain is a prevalent symptom at the end of life and negatively impacts quality of life. Despite this, little population level data exist that describe pain frequency and associated factors at the end of life. The purpose of this study was to explore the prevalence of clinically significant pain at the end of life and identify predictors of increased pain.

methodsRetrospective population-level cohort study of all decedents in Ontario, Canada, from April 1, 2011 to March 31, 2015 who received a home care assessment in the last 30 days of life (n = 20,349). Severe daily pain in the last 30 days of life using linked Ontario health administrative databases. Severe pain is defined using a validated pain scale combining pain frequency and intensity: daily pain of severe intensity.

resultsSevere daily pain was reported in 17.2% of 20,349 decedents. Increased risk of severe daily pain was observed in decedents who were female, younger and functionally impaired. Those who were cognitively impaired had a lower risk of reporting pain. Disease trajectory impacted pain; those who died of a terminal illness (i.e. cancer) were more likely to experience pain than those with frailty (odds ratio 1.66).

conclusionPain is a common fear of those contemplating end of life, but severe pain is reported in less than 1 in 5 of our population in the last month of life. Certain subpopulations may be more likely to report severe pain at the end of life and may benefit from earlier palliative care referral and intervention.

Indexed as

DeathAdolescentAdultAgedAged, 80 and overChildCohort StudiesFemaleHumansLogistic ModelsMaleMiddle AgedOntarioPainRetrospective StudiesEnd-of-lifePainPalliative carePalliative homecarePalliative medicine

Identifiers

PMID32354364
PMCPMC7193354
OpenAlexW3021100519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.