ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2020
4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Aortic Valve Phenotype Shapes Helical Flow in the Ascending Aorta: Insights from 4D Flow MRI.Annals of biomedical engineering · 2026Article
- Clinical Application of 4D Flow Cardiac Magnetic Resonance for Evaluating Complications After Surgical Aortic Valve Prosthesis Implantation.JACC. Case reports · 2025Article
- Cluster analysis of 100 Marfan patients based on aortic 4D flow MRI and Z-score: insights into disease heterogeneity and stratification of subgroups.European radiology · 2025Article
- Restoration of 3-dimensional aortic hemodynamics after the Ross procedure for unicuspid aortic valve disease using 4-dimensional flow magnetic resonance imaging.JTCVS structural and endovascular · 2025Article
- Article
- Blood flow assessment technology in aortic surgery: a narrative review.Journal of thoracic disease · 2024Review
- Restoration of flow in the aorta: a novel therapeutic target in aortic valve intervention.Nature reviews. Cardiology · 2024Review
- Four-Dimensional Flow Echocardiography: Blood Speckle Tracking in Congenital Heart Disease: How to Apply, How to Interpret, What Is Feasible, and What Is Missing Still.Healthcare (Basel, Switzerland) · 2024Review
- Longitudinal follow-up by MR angiography reveals progressive dilatation of the distal aorta after aortic root replacement in Marfan syndrome.European radiology · 2023Article
- Clinical Use of Blood Flow Analysis through 4D-Flow Imaging in Aortic Valve Disease.Journal of cardiovascular development and disease · 2023Review
- Fetal 4D flow MRI of the great thoracic vessels at 3 Tesla using Doppler-ultrasound gating: a feasibility study.European radiology · 2023Article
- Validation of 4D flow cardiovascular magnetic resonance in TIPS stent grafts using a 3D-printed flow phantom.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- Four-dimensional magnetic resonance after ascending aorta replacement and aortic valve repair with HAART 300 internal annuloplasty ring.Journal of cardiac surgery · 2022Article
- Aortic regurgitation: A multimodality approach.Journal of clinical ultrasound : JCU · 2022Review
- The role of 4-dimensional flow in the assessment of bicuspid aortic valve and its valvulo-aortopathies.The British journal of radiology · 2022Review
- Quantitative evaluation of aortic valve regurgitation in 4D flow cardiac magnetic resonance: at which level should we measure?BMC medical imaging · 2022Article
- Is there a role for angiotensin II-receptor blockers for ascending aorta dilatation in pediatric patients with normally functioning bicuspid aortic valve?International journal of cardiology. Congenital heart disease · 2022Article
- Clinical implications of the biomechanics of bicuspid aortic valve and bicuspid aortopathy.Frontiers in cardiovascular medicine · 2022Review
- Magnetic resonance angiography derived predictors of progressive dilatation and surgery of the aortic root in Marfan syndrome.PloS one · 2022Article
- Geometric characteristics of bicuspid aortic valves.JTCVS techniques · 2021Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAortic valve repair has become a treatment option for adults with symptomatic bicuspid (BAV) or unicuspid (UAV) aortic valve insufficiency. Our aim was to demonstrate the feasibility of 4D flow cardiovascular magnetic resonance (CMR) to assess the impact of aortic valve repair on changes in blood flow dynamics in patients with symptomatic BAV or UAV.
methodsTwenty patients with adult congenital heart disease (median 35 years, range 18-64; 16 male) and symptomatic aortic valve regurgitation (15 BAV, 5 UAV) were prospectively studied. All patients underwent 4D flow CMR before and after aortic valve repair. Aortic valve regurgitant fraction and systolic peak velocity were estimated. The degree of helical and vortical flow was evaluated according to a 3-point scale. Relative flow displacement and wall shear stress (WSS) were quantified at predefined levels in the thoracic aorta.
resultsAll patients underwent successful aortic valve repair with a significant reduction of aortic valve regurgitation (16.7 ± 9.8% to 6.4 ± 4.4%, p < 0.001) and systolic peak velocity (2.3 ± 0.9 to 1.9 ± 0.4 m/s, p = 0.014). Both helical flow (1.6 ± 0.6 vs. 0.9 ± 0.5, p < 0.001) and vortical flow (1.2 ± 0.8 vs. 0.5 ± 0.6, p = 0.002) as well as both flow displacement (0.3 ± 0.1 vs. 0.25 ± 0.1, p = 0.031) and WSS (0.8 ± 0.2 N/m
conclusions4D flow CMR allows assessment of the impact of aortic valve repair on changes in blood flow dynamics in patients with bicuspid aortic valve disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.