Evidence map›Paper›PMID 32354174›Full record

ReviewInternational journal of molecular sciences2020

Vitamin D as a Potential Therapy for Multiple Sclerosis: Where Are We?

Samiksha Wasnik, Isha Sharma, David J Baylink, Xiaolei Tang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. An Overview of Multiple Sclerosis In Vitro Models.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Article
  7. Magnesium and the Brain: A Focus on Neuroinflammation and Neurodegeneration.International journal of molecular sciences · 2022
    Review
  8. Inflammation- and Gut-Homing Macrophages, Engineered toInternational journal of molecular sciences · 2021
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Samiksha WasnikDivision of Regenerative Medicine, Department of Medicine, Loma Linda University, Loma Linda, CA 92350, USA.ORCID 0000-0001-6097-0517
Isha SharmaDepartment of Pathology & Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0003-3936-914X
David J BaylinkDivision of Regenerative Medicine, Department of Medicine, Loma Linda University, Loma Linda, CA 92350, USA.
Xiaolei TangDepartment of Veterinary Biomedical Sciences, College of Veterinary Medicine, Long Island University, Brookville, NY 11548, USA.ORCID 0000-0003-1492-9622
Loma Linda University · USLong Island University · USNorthwestern University · US

Funding

Targeting Intestinal Stem Cells to Augment the Repair of Epithelial BarrierR21AI142170 · NIAID · LONG ISLAND UNIVERSITY C. W. POST CENTER · PI TANG, XIAOLEI · 2019 to 2020
$456k
Loma Linda University 681207-2967, 681205-2967, and 325491NIH HHS R21AI142170U.S. Department of Defense W81XWH-15-1-0240
6 · The paper itself

Abstract

Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system and is caused by an aberrant immune response to myelin sheath. Disease-modifying medications, which mainly aim to suppress such aberrant immune response, have significantly improved MS treatment. However, the disease severity continues to worsen. In contrast, progressively more data suggest that 1,25-dihydroxyvitamin D or 1,25(OH)

Indexed as

AnimalsClinical Trials as TopicEncephalomyelitis, Autoimmune, ExperimentalHumansMultiple SclerosisSeverity of Illness IndexT-Lymphocytes, RegulatoryTreatment OutcomeVitamin DVitamin D1,25(OH)2Dexperimental autoimmune encephalomyelitishypercalcemiamultiple sclerosisvitamin D

Identifiers

PMID32354174
PMCPMC7247155
OpenAlexW3021423346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.