Evidence map›Paper›PMID 32354143›Full record

ArticleCancers2020

Genetic and Immune Changes Associated with Disease Progression under the Pressure of Oncolytic Therapy in A Neuroblastoma Outlier Patient.

Lidia Franco-Luzón, Sandra García-Mulero, Rebeca Sanz-Pamplona, Gustavo Melen, David Ruano, Álvaro Lassaletta, Luís Madero, África González-Murillo, Manuel Ramírez

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Celastrol promotes apoptotic cell death in children neuroblastoma cells through caspases dependent pathway.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2022
    Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Lidia Franco-LuzónChildren Oncohematology Foundation, 28079 Madrid, Spain.
Sandra García-MuleroDepartment of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0003-4931-1267
Rebeca Sanz-PamplonaUnit of Biomarkers and Susceptibility, Oncology Data Analytics Program (ODAP), Catalan Institute of Oncology (ICO), Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL) and CIBERESP, L'Hospitalet de Llobregat, 08908 Barcelona, Spain.ORCID 0000-0002-2187-3527
Gustavo MelenBiomedical Research Foundation, Niño Jesús Children Hospital, 28009 Madrid, Spain.
David RuanoLa Princesa Institute of Health Research, 28006 Madrid, Spain.
Álvaro LassalettaLa Princesa Institute of Health Research, 28006 Madrid, Spain.
Luís MaderoChildren Oncohematology Foundation, 28079 Madrid, Spain.
África González-MurilloBiomedical Research Foundation, Niño Jesús Children Hospital, 28009 Madrid, Spain.
Manuel RamírezBiomedical Research Foundation, Niño Jesús Children Hospital, 28009 Madrid, Spain.ORCID 0000-0003-0332-6973
Hospital Infantil Universitario Niño Jesús · ESHospital Universitario de La Princesa · ESInstitut d'Investigació Biomédica de Bellvitge · ES

Funding

Asociación NEN Celyvir: Viro-Inmunoterapia para niños con tumores metastásicos refractarios: del laboratorio a la clínica.Asociación Pablo Ugarte Inmunoterapia. Virus oncolíticos. Estudio CELYVIR.Fundación Neuroblastoma Celyvir: Viro-inmunoterapia para niños con neuroblastomas refractarios: del laboratorio a la clínica.Instituto de Salud Carlos III PI13/02487Instituto de Salud Carlos III PI16/02008
6 · The paper itself

Abstract

Little is known about the effect of oncolytic adenovirotherapy on pediatric tumors. Here we present the clinical case of a refractory neuroblastoma that responded positively to

Indexed as

bioinformatic analysisimmune landscapeKeywords: neuroblastomaoncolytic virotherapyT lymphocytes (TILs)

Identifiers

PMID32354143
PMCPMC7281487
OpenAlexW3021052601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.