Evidence map›Paper›PMID 32354121›Full record

ArticleInternational journal of molecular sciences2020

The Cannabinoid Receptor CB1 Stabilizes Sperm Chromatin Condensation Status During Epididymal Transit by Promoting Disulphide Bond Formation.

Teresa Chioccarelli, Francesco Manfrevola, Veronica Porreca, Silvia Fasano, Lucia Altucci, Riccardo Pierantoni, Gilda Cobellis

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  4. Metabolomic Analysis of Cauda Epididymal Fluid in Yaks and Cattle.Animals : an open access journal from MDPI · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Teresa ChioccarelliDepartment of Experimental Medicine, Sez. Bottazzi, Università degli Studi della Campania "L. Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy.ORCID 0000-0002-1720-1496
Francesco ManfrevolaDepartment of Experimental Medicine, Sez. Bottazzi, Università degli Studi della Campania "L. Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy.
Veronica PorrecaDepartment of Experimental Medicine, Sez. Bottazzi, Università degli Studi della Campania "L. Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy.
Silvia FasanoDepartment of Experimental Medicine, Sez. Bottazzi, Università degli Studi della Campania "L. Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy.
Lucia AltucciDepartment of Precision Medicine, Università degli Studi della Campania "L. Vanvitelli", Via L. De Crecchio 7, 80138 Napoli, Italy.ORCID 0000-0002-7312-5387
Riccardo PierantoniDepartment of Experimental Medicine, Sez. Bottazzi, Università degli Studi della Campania "L. Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy.ORCID 0000-0001-8246-2177
Gilda CobellisDepartment of Experimental Medicine, Sez. Bottazzi, Università degli Studi della Campania "L. Vanvitelli", Via Costantinopoli 16, 80138 Napoli, Italy.ORCID 0000-0001-5884-9208
University of Campania "Luigi Vanvitelli" · IT

Funding

Italian Ministry of University and Research PRIN to R. Pierantoni 2017Università degli Studi della Campania Dip. Medicina Sperimentale-2017 to G. CobellisUniversità degli Studi della Campania VALERE, Vanvitelli per la Ricerca 2019 to G. Cobellis
6 · The paper itself

Abstract

The cannabinoid receptor CB1 regulates differentiation of spermatids. We recently characterized spermatozoa from

Indexed as

AcetylationAnimalsBromodomain Containing ProteinsChromatinChromatin Assembly and DisassemblyCo-Repressor ProteinsDisulfidesEpididymisGene DeletionGene Expression RegulationGene Knockout TechniquesHistonesHydro-LyasesMaleMiceNuclear ProteinsBRDT protein, mouseBromodomain Containing ProteinsCdyl protein, mouseChromatinCNR1 protein, mouseCo-Repressor ProteinsDisulfidesHistonesHydro-LyasesNuclear ProteinsReceptor, Cannabinoid, CB1bromodomain protein BRDTcaput and cauda epididymischromatin remodeling and histone displacementchromodomain protein CDYLestrogens and endocannabinoidspost-translational modification of histone H4 (histone H4 acetylation)protamine thiol oxidationsperm chromatin condensation and maturationspermiogenesistype-1 cannabinoid receptor (CB1)

Identifiers

PMID32354121
PMCPMC7247701
OpenAlexW3023787341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.