Evidence map›Paper›PMID 32354113›Full record

ReviewNanomaterials (Basel, Switzerland)2020

On Facing the SARS-CoV-2 (COVID-19) with Combination of Nanomaterials and Medicine: Possible Strategies and First Challenges.

Vishnu Sankar Sivasankarapillai, Akhilash M Pillai, Abbas Rahdar, Anumol P Sobha, Sabya Sachi Das, Athanasios C Mitropoulos, Mahboobeh Heidari Mokarrar, George Z Kyzas

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Nanoparticles as an effective drug delivery system in COVID-19.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
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  7. Silver, Its Salts and Application in Medicine and Pharmacy.International journal of molecular sciences · 2023
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  19. Niclosamide encapsulated in mesoporous silica and geopolymer: A potential oral formulation for COVID-19.Microporous and mesoporous materials : the official journal of the International Zeolite Association · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vishnu Sankar SivasankarapillaiDepartment of Chemistry, NSS Hindu College, Changanacherry, Kerala 686102, India.
Akhilash M PillaiDepartment of Chemistry, University College, Thiruvananthapuram, Kerala 695034, India.
Abbas RahdarDepartment of Physics, University of Zabol, Zabol 98615538, Iran.
Anumol P SobhaDepartment of Biochemistry, University of Kerala, Thiruvananthapuram, Kerala 695581, India.
Sabya Sachi DasDepartment of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi, Jharkhand 835215, India.
Athanasios C MitropoulosDepartment of Chemistry, International Hellenic University, Kavala 65404, Greece.
Mahboobeh Heidari MokarrarDepartment of English Language, Education office of Zahedan District 2, Zahedan 9817888741, Iran.
George Z KyzasDepartment of Chemistry, International Hellenic University, Kavala 65404, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Global health is facing the most dangerous situation regarding the novel severe acute respiratory syndrome called coronavirus 2 (SARS-CoV-2), which is widely known as the abbreviated COVID-19 pandemic. This is due to the highly infectious nature of the disease and its possibility to cause pneumonia induced death in approximately 6.89% of infected individuals (data until 27 April 2020). The pathogen causing COVID-19 is called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which is believed to be originated from the Wuhan Province in China. Unfortunately, an effective and approved vaccine for SARS-CoV-2 virus is still not available, making the situation more dangerous and currently available medical care futile. This unmet medical need thus requires significant and very urgent research attention to develop an effective vaccine to address the SARS-CoV-2 virus. In this review, the state-of-the-art drug design strategies against the virus are critically summarized including exploitations of novel drugs and potentials of repurposed drugs. The applications of nanochemistry and general nanotechnology was also discussed to give the status of nanodiagnostic systems for COVID-19.

Indexed as

coronavirusCOVID-19medicinal chemistrypublic healthSARS-CoV-2theranostic strategies

Identifiers

PMID32354113
PMCPMC7712148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.