Evidence map›Paper›PMID 32354078›Full record

ArticleMolecules (Basel, Switzerland)2020

Differential Proliferation Effect of the Newly Synthesized Valine, Tyrosine and Tryptophan-Naphthoquinones in Immortal and Tumorigenic Cervical Cell Lines.

Sergio Córdova-Rivas, Jorge Gustavo Araujo-Huitrado, Ernesto Rivera-Avalos, Ismailia L Escalante-García, Sergio M Durón-Torres, Yamilé López-Hernández, Hiram Hernández-López, Lluvia López, Denisse de Loera, Jesús Adrián López

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Synthesis of Novel Fluoro Phenyl TriazolesCurrent organic synthesis · 2024
    Article
  4. Differential Effect of 4Current medicinal chemistry · 2024
    Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sergio Córdova-RivasLaboratorio de microRNAs y Cáncer, Unidad Académica de Ciencias Biológicas, Universidad Autónoma de Zacatecas, Zacatecas 98068, Mexico.
Jorge Gustavo Araujo-HuitradoLaboratorio de microRNAs y Cáncer, Unidad Académica de Ciencias Biológicas, Universidad Autónoma de Zacatecas, Zacatecas 98068, Mexico.
Ernesto Rivera-AvalosSchool of Chemistry, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78210, Mexico.
Ismailia L Escalante-GarcíaUnidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0000-0001-7193-6875
Sergio M Durón-TorresUnidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Yamilé López-HernándezCONACYT, Laboratorio de Metabolómica y Proteómica, Unidad Académica de Ciencias Biológicas, Universidad Autónoma de Zacatecas, Zacatecas 98068, Mexico.ORCID 0000-0002-1068-603X
Hiram Hernández-LópezUnidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.ORCID 0000-0002-4286-163X
Lluvia LópezInstituto de Investigación de Zonas Desérticas, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78377, Mexico.ORCID 0000-0002-6408-3306
Denisse de LoeraSchool of Chemistry, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78210, Mexico.
Jesús Adrián LópezLaboratorio de microRNAs y Cáncer, Unidad Académica de Ciencias Biológicas, Universidad Autónoma de Zacatecas, Zacatecas 98068, Mexico.ORCID 0000-0001-8012-7041
Universidad Autónoma de Zacatecas "Francisco García Salinas" · MXAutonomous University of San Luis Potosí · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously showed that microwave assisted synthesis is the best method for the synthesis of naphthoquinone amino acid and chloride-naphthoquinone amino acid derivatives by a complete evaluation of reaction conditions such as stoichiometry, bases, and pH influence. Following the same strategy, we synthesized chloride and non-chloride tyrosine, valine, and tryptophan-naphthoquinones achieving 85-95%, 80-92%, and 91-95% yields, respectively. The cyclic voltammetry profiles showed that both series of naphthoquinone amino acid derivatives mainly display one redox reaction process. Overall, chloride naphthoquinone amino acid derivatives exhibited redox potential values (E

Indexed as

Antineoplastic AgentsCarcinogenesisCell Line, TumorCell ProliferationChloridesDrug DesignDrug Screening Assays, AntitumorFemaleHaCaT CellsHumansInhibitory Concentration 50MicrowavesNaphthoquinonesOxidation-ReductionPapillomavirus InfectionsTryptophanAntineoplastic AgentsChloridesNaphthoquinonesTryptophanTyrosineValinealternative methodsamino acidsanticancermicrowavenaphthoquinoneultrasound

Identifiers

PMID32354078
PMCPMC7248809
OpenAlexW3022781771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.