Coupling of Bioreaction and Separation via Novel Thermosensitive Ionic Liquids Applied in the Baker's Yeast-Catalyzed Reduction of Ethyl 2-oxo-4-phenylbutyrate.

Yuexi Yang, Yugang Shi, Lifang Feng, Shiyi Tian

Open access · goldAbstract read

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Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.3field-weighted citation impact, top 47% of its field

1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed, 3 citations in OpenAlex.

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5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuexi YangSchool of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.

Yugang ShiSchool of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.

Lifang FengSchool of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.

Shiyi TianSchool of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.

Zhejiang Gongshang University · CN

Funding

Academic Exchanges and Talent Training Program 2017SICR109Foundation of Zhejiang Provincial Department of Education Y201737665National Natural Science Foundation of China 21106131Postdoctoral Fellowships Program of Zhejiang Province [2017]71-95Program for Overseas High-Level Experts Introduction Z20170407Zhejiang Province Public Welfare Technology Application Research Project LGJ19C200001Zhejiang Provincial Food Science and Engineering the Most Important Discipline JYTsp20142101

6 · The paper itself

Abstract

The use of baker's yeast to reduce ethyl 2-oxo-4-phenylbutyrate (EOPB) in conventional biphasic systems is hindered by low productivities due to mass transfer resistance between the biocatalyst and the substrate partitioned into two different phases. To overcome the limitation, a new reaction-separation coupling process (RSCP) was configured in this study, based on the novel thermosensitive ionic liquids (ILs) with polyoxyethylene-tail. The solubility of ILs in common solvents was investigated to configure the unique thermosensitive ionic liquids-solvent biphasic system (TIBS) in which the reduction was performed. [(CH

Indexed as

Ionic LiquidsBiocatalysisCatalysisChloridesGreen Chemistry TechnologyPhenylbutyratesPolyethylene GlycolsSaccharomyces cerevisiaeSolubilitySolventsStereoisomerismTemperatureWater4-phenylbutyric acidChloridesethyl 2-oxo-4-phenylbutyrateIonic LiquidsPhenylbutyratesPolyethylene GlycolsSolventsWaterbaker’s yeast-catalyzed reductioncoupled bioreaction and separationethyl 2-oxo-4-phenylbutyrateethyl (R)-2-hydroxy-4-phenylbutyratethermosensitive ionic liquids–solvent biphasic system

Identifiers

PMID32354057

DOI10.3390/molecules25092056

PMCPMC7249150

OpenAlexW3022137829

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.