ArticleEpilepsia2020
Severe psychological distress among patients with epilepsy during the COVID-19 outbreak in southwest China.
Article in Epilepsia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 7 of them syntheses that pooled it.
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Who cites it
85 citing papers in PubMed, 7 syntheses or guidelines pooled it, 141 citations in OpenAlex.
- Prevalence of depression, anxiety, and psychological distress in patients with epilepsy during COVID-19: A systematic review.Epilepsy & behavior : E&B · 2021Pooled it
- Epilepsy and the risk of severe coronavirus disease 2019 outcomes: A systematic review, meta-analysis, and meta-regression.Epilepsy & behavior : E&B · 2021Pooled it
- Mental burden and its risk and protective factors during the early phase of the SARS-CoV-2 pandemic: systematic review and meta-analyses.Globalization and health · 2021Pooled it
- COVID-19, de novo seizures, and epilepsy: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Pooled it
- A Systematic Review on Sex- and Gender-Sensitive Research in Public Mental Health During the First Wave of the COVID-19 Crisis.Frontiers in psychiatry · 2021Pooled it
- The psychological and mental impact of coronavirus disease 2019 (COVID-19) on medical staff and general public - A systematic review and meta-analysis.Psychiatry research · 2020Pooled it
- Pooled it
- Assessing the Fear of Covid-19 in Psychiatric Patients: Results from an Italian Multicentric Study.Clinical neuropsychiatry · 2024Article
- Bibliometric analysis of research in epilepsy and comorbid depression from 2014 to 2023.World journal of psychiatry · 2024Article
- Frequency and risk factors of psychological distress among individuals with epilepsy before and during the outbreak of the SARS-CoV-2 Omicron variant in China: an online questionnaire survey.Acta epileptologica · 2024Article
- Epilepsy in Asian countries.Acta epileptologica · 2023Review
- Epilepsy-related mortality during the COVID-19 pandemic: A nationwide study of routine Scottish data.Seizure · 2023Article
- Interaction between COVID-19 and epilepsy during the omicron surge: A cross-sectional survey conducted in China tertiary hospital.Epilepsy & behavior reports · 2023Article
- Long-term analysis of the effects of COVID-19 in people with epilepsy: Results from a multicenter on-line survey across the pandemic waves.Epilepsy & behavior : E&B · 2022Article
- Effect of the pandemic on surgical procedures in a tertiary care hospital: A retrospective review.Turkish journal of surgery · 2022Article
- Seizure control during the COVID-19 pandemic: Correlating Responsive Neurostimulation System data with patient reports.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2022Article
- A Genetic Model of Epilepsy with a Partial Alzheimer's Disease-Like Phenotype and Central Insulin Resistance.Molecular neurobiology · 2022Article
- Psychological sequelae within different populations during the COVID-19 pandemic: a rapid review of extant evidence.Singapore medical journal · 2022Review
- A longitudinal seizure outcome following the COVID-19 pandemic in 2020 and 2021: Transient exacerbation or sustainable mitigation.Journal of the neurological sciences · 2022Article
- The impact of one-year COVID-19 containment measures in patients with mesial temporal lobe epilepsy: A longitudinal survey-based study.Epilepsy & behavior : E&B · 2022Article
25 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo compare the severity of psychological distress between patients with epilepsy and healthy controls during the COVID-19 outbreak in southwest China, as well as identify potential risk factors of severe psychological distress among patients with epilepsy.
methodsThis cross-sectional case-control study examined a consecutive sample of patients older than 15 years treated at the epilepsy center of West China Hospital between February 1 and February 29, 2020. As controls, sex- and age-matched healthy visitors of inpatients (unrelated to the patients) were also enrolled during the same period. Data on demographics and attention paid to COVID-19 were collected by online questionnaire, data on epilepsy features were collected from electronic medical records, and psychological distress was evaluated using the 6-item Kessler Psychological Distress Scale (K-6). Potential risk factors of severe psychological distress were identified using multivariate logistic regression.
resultsThe 252 patients and 252 controls in this study were similar along all demographic variables except family income. Patients with epilepsy showed significantly higher K-6 scores than healthy controls and spent significantly more time following the COVID-19 outbreak (both P < .001). Univariate analyses associated both diagnosis of drug-resistant epilepsy and time spent paying attention to COVID-19 with severe psychological distress (defined as K-6 score >12; both P ≤ .001). Multivariate logistic regression identified two independent predictors of severe psychological distress: time spent paying attention to COVID-19 (odds ratio [OR] = 1.172, 95% confidence interval [CI] = 1.073-1.280) and diagnosis of drug-resistant epilepsy (OR = 0.283, 95% CI = 0.128-0.623). SIGNIFICANCE: During public health outbreaks, clinicians and caregivers should focus not only on seizure control but also on mental health of patients with epilepsy, especially those with drug-resistant epilepsy. K-6 scores > 12 indicate severe psychological distress. This may mean, for example, encouraging patients to engage in other activities instead of excessively following media coverage of the outbreak.
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