SynthesisJournal of child psychology and psychiatry, and allied disciplines2021
Research Review: Conflicts of Interest (COIs) in autism early intervention research - a meta-analysis of COI influences on intervention effects.
Synthesis in Journal of child psychology and psychiatry, and allied disciplines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Invisible Harms, Visible Benefits? Adverse Event Reporting in Physical Activity Interventions for Neurodevelopmental Disorders: A Meta-analysis and Critical Appraisal.Sports medicine - open · 2026Pooled it
- Benefits and harms of interventions to improve anxiety, depression, and other mental health outcomes for autistic people: A systematic review and network meta-analysis of randomised controlled trials.Autism : the international journal of research and practice · 2023Pooled it
- Institutional conflicts of interest in health-related research - a scoping review.Research integrity and peer review · 2026Article
- Strategizing AI utilization for psychological literature screening: A comparative analysis of machine learning algorithms and key factors to consider.Research synthesis methods · 2026Article
- Avoiding Abuse of Power: A Case for Compassionate, Participant-Centered Research.Behavior analysis in practice · 2026Article
- Integration of specialized residential interventions with community-based services for autistic adults with severe challenging behaviors: preliminary evidence from the Piedmont model.Frontiers in psychiatry · 2026Article
- Maximizing the Quality and Reporting Standards of Autism Intervention Science.Autism research : official journal of the International Society for Autism Research · 2025Article
- The Social Validity of Behavioral Interventions: Seeking Input from Autistic Adults.Journal of autism and developmental disorders · 2025Article
- Adverse childhood experiences exacerbate peripheral symptoms of autism spectrum disorder in adults.Psychiatry and clinical neurosciences · 2024Article
- Evidence-b(i)ased practice: Selective and inadequate reporting in early childhood autism intervention research.Autism : the international journal of research and practice · 2024Review
- Social Validity of Pivotal Response Treatment for Young Autistic Children: Perspectives of Autistic Adults.Journal of autism and developmental disorders · 2024Article
- 'The best way to get it right is to listen to us' - autistic people argue for a stronger voice in research.Nature · 2023Article
- Mindshift in autism: a call to professionals in research, clinical, and educational settings.Frontiers in psychiatry · 2023Article
- Addressing the autism mental health crisis: the potential of phenomenology in neurodiversity-affirming clinical practices.Frontiers in psychology · 2023Article
- Neurodiversity and Autism Intervention: Reconciling Perspectives Through a Naturalistic Developmental Behavioral Intervention Framework.Journal of autism and developmental disorders · 2022Article
- Autistic Perspectives on the Future of Clinical Autism Research.Autism in adulthood · 2022Article
- Evaluating Interactive Language for Children with Autism Spectrum Disorder (ASD) in Different Contexts.Children (Basel, Switzerland) · 2022Article
- The Neurodiversity Approach(es): What Are They and What Do They Mean for Researchers?Human development · 2022Article
- Searching for What Really Matters: A Thematic Analysis of Quality of Life among Preschool Children on the Autism Spectrum.Journal of autism and developmental disorders · 2022Article
- Annual Research Review: Shifting from 'normal science' to neurodiversity in autism science.Journal of child psychology and psychiatry, and allied disciplines · 2022Review
Corrections and comments
- Commented on by
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe presence, types, disclosure rates, and effects of conflicts of interest (COIs) on autism early intervention research have not previously been studied. The purpose of this study was to examine these issues.
methodsThis study is a secondary analysis of a comprehensive meta-analysis of all group-design, nonpharmacological early intervention autism research conducted between 1970 and 2018. We coded reports for the presence/absence of COI statements, the types of COIs that were disclosed, and for 8 types of COIs, including (a) the author developed the intervention, (b) the author is affiliated with a clinical provider, (c) the author is employed by a clinical provider, (d) the author is affiliated with an institution that trains others to use the intervention, (e) the author receives payment or royalties related to the intervention, (f) the study was funded by an intervention provider, (g) the study used a commercially available measure developed by the author, and (h) proceeds of the intervention fund the author's research. Frequencies and proportions were calculated to determine prevalence of COIs and COI disclosures. Meta-analysis was used to estimate summary effects by COI type and to determine if they were larger than for reports with no coded COIs.
resultsSeventy percent of reports were coded for ≥ 1 COI, but only ~ 6% of reports contained COI statements fully accounting for all coded COIs. Metaregressions did not detect significant influences of any COI type on summary effects; however, point estimates for each COI type were larger than for reports with no coded COIs.
conclusionsConflicts of interest are prevalent but under-reported in autism early intervention research. Improved reporting practices are necessary for researcher transparency and would enable more robust examination of the effects of COIs on research outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.