Evidence map›Paper›PMID 32352849›Full record

ArticleGut microbes2020

Gut microbiota derived metabolites contribute to intestinal barrier maturation at the suckling-to-weaning transition.

Martin Beaumont, Charlotte Paës, Eloïse Mussard, Christelle Knudsen, Laurent Cauquil, Patrick Aymard, Céline Barilly, Béatrice Gabinaud, Olivier Zemb, Sandra Fourre and 6 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it, 125 citations in OpenAlex.

  1. Pooled it
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  15. Effects ofFrontiers in veterinary science · 2025
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Martin BeaumontGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.ORCID 0000-0002-1559-2067
Charlotte PaësGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.
Eloïse MussardGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.
Christelle KnudsenGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.ORCID 0000-0002-9587-8179
Laurent CauquilGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.ORCID 0000-0002-0384-8811
Patrick AymardGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.
Céline BarillyGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.
Béatrice GabinaudGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.
Olivier ZembGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.ORCID 0000-0003-3900-5522
Sandra FourreGeT-PlaGe, Genotoul, INRAE , Toulouse, France.
Roselyne GautierToxalim (Research Centre in Food Toxicology), Université De Toulouse, INRAE, ENVT, INP-Purpan, UPS , Toulouse, France.
Corinne LencinaToxalim (Research Centre in Food Toxicology), Université De Toulouse, INRAE, ENVT, INP-Purpan, UPS , Toulouse, France.
Hélène EutamèneToxalim (Research Centre in Food Toxicology), Université De Toulouse, INRAE, ENVT, INP-Purpan, UPS , Toulouse, France.
Vassilia TheodorouToxalim (Research Centre in Food Toxicology), Université De Toulouse, INRAE, ENVT, INP-Purpan, UPS , Toulouse, France.
Cécile CanletToxalim (Research Centre in Food Toxicology), Université De Toulouse, INRAE, ENVT, INP-Purpan, UPS , Toulouse, France.
Sylvie CombesGenPhySE, Université De Toulouse, INRAE, ENVT , Toulouse, France.ORCID 0000-0002-2945-4423
École Nationale Vétérinaire de Toulouse · FRUniversité Toulouse III - Paul Sabatier · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In suckling mammals, the onset of solid food ingestion is coincident with the maturation of the gut barrier. This ontogenic process is driven by the colonization of the intestine by the microbiota. However, the mechanisms underlying the microbial regulation of the intestinal development in early life are not fully understood. Here, we studied the co-maturation of the microbiota (composition and metabolic activity) and of the gut barrier at the suckling-to-weaning transition by using a combination of experiments

Indexed as

EatingWeaningAnimalsAnimals, SucklingBacteriaCaco-2 CellsCecumGastrointestinal MicrobiomeGene Expression RegulationGenes, rRNAHumansIntestinal MucosaMaleMilkOrganoidsPermeabilityRNA, Ribosomal, 16SEarly lifeepitheliumintestinal barrier developmentmaternal milkmetabolomeorganoidssolid food

Identifiers

PMID32352849
PMCPMC7524271
OpenAlexW3023681233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.