Evidence map›Paper›PMID 32352741›Full record

ArticleACS nano2020

Acoustofluidics-Assisted Engineering of Multifunctional Three-Dimensional Zinc Oxide Nanoarrays.

Nanjing Hao, Pengzhan Liu, Hunter Bachman, Zhichao Pei, Peiran Zhang, Joseph Rufo, Zeyu Wang, Shuaiguo Zhao, Tony Jun Huang

Abstract read
In one paragraph

Article in ACS nano, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. SERS-Based Nano- and Microsystems Toward Biomedical Applications.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  2. Review
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  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
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  10. Acoustics-Actuated Microrobots.Micromachines · 2022
    Review
  11. Article
  12. Recent developments in isolating methods for exosomes.Frontiers in bioengineering and biotechnology · 2022
    Review
  13. Acoustofluidics-Assisted Fluorescence-SERS Bimodal Biosensors.Small (Weinheim an der Bergstrasse, Germany) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nanjing HaoDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0003-3808-7941
Pengzhan LiuDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.
Hunter BachmanDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.
Zhichao PeiDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.
Peiran ZhangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0002-3873-9949
Joseph RufoDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.
Zeyu WangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.
Shuaiguo ZhaoDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.
Tony Jun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0003-1205-3313

Funding

Integrated Acoustofluidic Plasmonic Molecular Diagnostic System for Detecting MicroRNA BiomarkersR01GM135486 · NIGMS · DUKE UNIVERSITY · PI VO-DINH, TUAN · 2020 to 2023
$1.8M
Acoustofluidic Separation (AFS), Purification and Raman Spectral Fingerprinting of Single EVs: From Cell of Origin to Target Cell and BiofluidsUG3TR002978 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AN, JI YEONG, GALL, KENNETH A · 2019 to 2020
$823k
An acoustofluidic device for diagnosing preclinical Alzheimer's diseaseR43AG063643 · NIA · ASCENT BIO-NANO TECHNOLOGIES, INC. · PI WANG, LIN · 2019 to 2019
$225k
NCATS NIH HHS UG3 TR002978NIA NIH HHS R43 AG063643NIGMS NIH HHS R01 GM135486
6 · The paper itself

Abstract

The integration of acoustics and microfluidics (termed acoustofluidics) presents a frontier in the engineering of functional micro-/nanomaterials. Acoustofluidic techniques enable active and precise spatiotemporal control of matter, providing great potential for the design of advanced nanosystems with tunable material properties. In this work, we introduce an acoustofluidic approach for engineering multifunctional three-dimensional nanostructure arrays and demonstrate their potential in enrichment and biosensing applications. In particular, our acoustofluidic device integrates an acoustic transducer with a sharp-edge-based acoustofluidic reactor that enables uniform patterning of zinc oxide (ZnO) nanoarrays with customizable lengths, densities, diameters, and other properties. The resulting ZnO nanoarray-coated glass capillaries can rapidly and efficiently capture and enrich biomolecules with sizes ranging from a few nanometers to several hundred nanometers. In order to enable the detection of these biomolecules, silver (Ag) nanoparticles are deposited onto the ZnO nanoarrays, and the integrated ZnO-Ag capillary device functions as a label-free plasmonic biosensing system for surface-enhanced Raman spectroscopy (SERS) based detection of exosomes, DNA oligonucleotides, and

Indexed as

NanostructuresZinc OxideEscherichia coliSilverSpectrum Analysis, RamanSilverZinc OxideacousticsacoustofluidicsmicrofluidicsSERS sensingZnO nanoarray

Identifiers

PMID32352741
PMCPMC7415004

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.