Observational studyClinical cardiology2020
Gender-specific association between body mass index and all-cause mortality in patients with atrial fibrillation.
Observational study in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Trends in Atrial Fibrillation-Related Mortality Among Adults With Obesity in the United States From 1999 to 2024.Obesity science & practice · 2026Article
- Alkaline Phosphatase to Albumin Ratio as a Novel Predictor of All-Cause Mortality in Critically Ill Patients With Atrial Fibrillation.Cardiology research and practice · 2025Article
- Associations Between Mid- to Late-Life Body Mass Index and Chronic Disease-Free Survival: A Nationwide Twin Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Associations of body mass index, fasting insulin, and inflammation with mortality: a prospective cohort study.International journal of obesity (2005) · 2022Article
- Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review.Journal of cachexia, sarcopenia and muscle · 2022Review
- A Simple Logistic Regression Model for Predicting the Likelihood of Recurrence of Atrial Fibrillation Within 1 Year After Initial Radio-Frequency Catheter Ablation Therapy.Frontiers in cardiovascular medicine · 2021Article
- Gender-specific association between body mass index and all-cause mortality in patients with atrial fibrillation.Clinical cardiology · 2020Observational
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundElevated body mass index (BMI) is related with reduced mortality in various cardiovascular diseases. HYPOTHESIS: Gender-specific association between BMI and mortality exists in atrial fibrillation (AF).
methodsIn this multicenter observational study with a mean follow-up of 1 year, a total of 1991 AF patients were enrolled and divided into two groups based on the gender. The primary endpoint was all-cause mortality while the secondary endpoints were defined as cardiovascular mortality, stroke, and major adverse events during 1-year follow-up. Cox regression was performed to identify the association between BMI and clinical outcomes according to gender.
resultsFemale patients with AF tended to be older (P = .027) and thinner (P < .001) than male patients with AF. They were more likely to have heart failure, hyperthyroidism, and valvular AF (all P < .05), but less likely to have coronary artery disease and prior myocardial infarction (all P < .01). Multivariate analysis revealed that overweight (HR(95%CI): 0.55(0.41-0.75), P < .001) and obese patients (HR(95%CI): 0.56(0.34-0.94), P = .028) were associated with significant lower all-cause mortality compared with normal weight patients for the entire cohort. Similar association between elevated BMI and reduced all-cause mortality were only identified in female patients with AF (overweight vs normal weight: HR(95%CI): 0.43(0.27-0.70); obesity vs normal weight: HR(95%CI): 0.46(0.22-0.97)), but not in male patients with AF.
conclusionThis study indicates that overweight and obesity were related with improved survival in patients with AF. The association between elevated BMI and reduced mortality was dependent on gender, which was only significant in female patients, rather than male patients.
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