Evidence map›Paper›PMID 32352575›Full record

ArticleJournal of medical virology2020

Comment on "The neuroinvasive potential of SARS-CoV-2 may play a role in the respiratory failure of COVID-19 patients".

Fatiha Chigr, Mohamed Merzouki, Mohamed Najimi

Registry-linked trialOpen access · bronzeAbstract readComment
In one paragraph

Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04632719 (MentalPlus® for Assessment and Rehabilitation of Cognitive Functions After Remission of Symptoms of COVID-19), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04632719 nacompletednot on this map

MentalPlus® for Assessment and Rehabilitation of Cognitive Functions After Remission of Symptoms of COVID-19

TypeinterventionalSponsorUniversity of Sao PauloRan2020 to 2023Enrolled200ConditionsCognitive Impairment, Covid19, Cognitive Dysfunction, Depression, AnxietyArmsThe use of the MentalPlus® digital game for assessment and rehabilitation of cognitive function after remission of the symptoms of COVID-19
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Update on the neurology of COVID-19.Journal of medical virology · 2020
    Article
  15. Article
  16. Part I. SARS-CoV-2 triggered 'PANIC' attack in severe COVID-19.Journal of the neurological sciences · 2020
    Review
  17. Review
  18. Obesity and COVID-19: Oro-Naso-Sensory Perception.Journal of clinical medicine · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fatiha ChigrLife Sciences Department, Bioengineering laboratory, Sultan Moulay Slimane University, Beni Mellal, Morocco.ORCID 0000-0002-6691-6906
Mohamed MerzoukiLife Sciences Department, Bioengineering laboratory, Sultan Moulay Slimane University, Beni Mellal, Morocco.
Mohamed NajimiLife Sciences Department, Bioengineering laboratory, Sultan Moulay Slimane University, Beni Mellal, Morocco.
Université Sultan Moulay Slimane · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have read with great care and interest the article by Li et al The authors provide interesting elements with respect to the possible entry of severe acute respiratory syndrome coronavirus 2 at the brain area and plead for an implication of the central nervous system in respiratory problems linked to coronavirus disease. Here we provide additional elements that support those observations, notably the role of brainstem structures located in the medulla oblongata in modulating respiration. We also discussed the possible pathways the virus uses to cross the brain blood barrier and reach the brainstem.

Indexed as

Respiratory InsufficiencySevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirusBetacoronavirusCoronavirus InfectionsCOVID-19HumansPandemicsPneumonia, ViralSARS-CoV-2central nervous systemcoronavirusCOVID-19respiratory tract

Identifiers

PMID32352575
PMCPMC7267316
OpenAlexW3023577255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.