Evidence map›Paper›PMID 32352423›Full record

ArticleLa Medicina del lavoro2020

Silicosis in finishing workers in quartz conglomerates processing.

Gabriella Guarnieri, Mauro Salasnich, Paolo Lucernoni, Marta Sbaraglia, Maria Grazia Putzu, Paolo Zuliani, Federica Rossi, Stefania Vio, Leonardo Bianchi, Andrea Martinelli and 5 more

Open access · diamondAbstract read
In one paragraph

Article in La Medicina del lavoro, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Gabriella GuarnieriDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Padua, Italy. gabriella.guarnieri@gmail.com.
Mauro SalasnichRespiratory Unit, Ca' Foncello Hospital, Azienda ULSS 2 Marca Trevigiana, Treviso, Italy. mauro.salasnich@aulss2.veneto.it.
Paolo LucernoniRespiratory Unit, Ca' Foncello Hospital, Azienda ULSS 2 Marca Trevigiana, Treviso, Italy. paolo.lucernoni@aulls2.veneto.it.
Marta SbaragliaPathology Unit, Ca' Foncello Hospital, Azienda ULSS 2 Marca Trevigiana, Treviso, Italy. marta.sbaraglia@aull2.veneto.it.
Maria Grazia PutzuDepartment of Public Health and Pediatric Sciences, University of Turin, Turin, Italy. mariagrazia.putzu62@gmail.com.
Paolo ZulianiDepartment of Public Health and Pediatric Sciences, University of Turin, Turin, Italy. pzuliani@cittadellasalute.to.it.
Federica RossiDepartment of Public Health and Pediatric Sciences, University of Turin, Turin, Italy. federica.rossi@unito.it.
Stefania VioRadiology Unit, University Hospital, Padua, Italy. stefania.vio@aopd.veneto.it.
Leonardo BianchiDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Padua, Italy. leonardo.bianchi30@gmail.com.
Andrea MartinelliDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Padua, Italy. andrea.martinelli@unipd.it.
Ottorino GottardoSPISAL, Azienda ULSS6 Euganea, Padua, Italy. ottorino.gottardo@aulss6.veneto.it.
Rosanna BizzottoSPISAL, Azienda ULSS6 Euganea, Padua, Italy. rosana.bizzotto@aulss6.veneto.it.
Piero MaestrelliDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Padua, Italy. piero.maestrelli@unipd.it.
Paola MasonDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Padua, Italy. paola.mason.1@unipd.it.
Mariella CarrieriDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Padua, Italy. mariella.carrieri@unipd.it.
University of Padua · ITAULSS 2 Marca Trevigiana · ITDepartment of Public Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOutbreaks of silicosis have bene recently reported in artificial stone workers.

aimTo describe the features of silicosis in quartz conglomerate workers in North-Eastern Italy.

methodsActive search of pneumoconiosis was performed in 11 companies of North-Eastern Italy involved in the fabrication of quartz conglomerate countertops. Occupational history, lung function tests, chest X-ray and high resolution computed tomography (HRCT) were performed. In selected cases, trans-bronchial biopsies were taken for histological evaluation and identification of silica crystals in the tissue. Cumulative exposure to crystalline silica was estimated.

resultsWe recruited 45 workers and 24 cases of silicosis were diagnosed. Mean age at diagnosis was 43 years and duration of exposure to quartz conglomerate dust was 3.5 to 20 years. The average silica cumulative exposure was 4.3 mg/m3/y. Abnormal findings were detected in 42% of chest X-rays, in 33% of spirometry and 50% of carbon monoxide lung diffusion (DLco). HRCTs were abnormal in all cases showing well-defined rounded opacities, irregular/linear intralobular opacities and bilateral enlarged mediastinal lymph-nodes. Histological findings consistent with silicosis were observed in 24 cases. Numerous silica particles (diameter 0.1-5 µm) were identified in lung tissue.

conclusionsWe reported an unexpected high incidence of silicosis in Italian workers exposed to quartz conglomerate dust. The results suggest that chest HRCT is indicated for screening of workers with high exposure to silica and DLco should be added to spirometry in health surveillance. More rigorous application of safety regulations and more effective preventive interventions at work are necessary.

Indexed as

Occupational ExposurePneumoconiosisQuartzSilicosisAdultDustHumansItalySilicon DioxideDustQuartzSilicon Dioxide

Identifiers

PMID32352423
PMCPMC7810008
OpenAlexW3021323737

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.