Evidence map›Paper›PMID 32352281›Full record

ArticleAnalytical chemistry2020

Photostable and Proteolysis-Resistant Förster Resonance Energy Transfer-Based Calcium Biosensor.

Dat Nguyen, Danielle M Behrens, Sanjana Sen, Avid Najdahmadi, Jessica N Pham, Gaetano Speciale, Micah M Lawrence, Sudipta Majumdar, Gregory A Weiss, Elliot L Botvinick

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Hydrogels and Their Role in Biosensing Applications.Advanced healthcare materials · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Dat NguyenDepartment of Biomedical Engineering, University of California, Irvine, California 92697-2730, United States.ORCID 0000-0001-5582-7222
Danielle M BehrensDepartment of Biomedical Engineering, University of California, Irvine, California 92697-2730, United States.
Sanjana SenDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California 92697-3900, United States.
Avid NajdahmadiBeckman Laser Institute and Medical Clinic, University of California, Irvine, California 92612-1475, United States.
Jessica N PhamDepartment of Chemistry, University of California, Irvine, California 92697-2015, United States.
Gaetano SpecialeDepartment of Chemistry, University of California, Irvine, California 92697-2015, United States.ORCID 0000-0001-6354-605X
Micah M LawrenceDepartment of Biomedical Engineering, University of California, Irvine, California 92697-2730, United States.
Sudipta MajumdarDepartment of Chemistry, University of California, Irvine, California 92697-2015, United States.
Gregory A WeissDepartment of Molecular Biology and Biochemistry, University of California, Irvine, California 92697-3900, United States.ORCID 0000-0003-0296-9846
Elliot L BotvinickDepartment of Biomedical Engineering, University of California, Irvine, California 92697-2730, United States.ORCID 0000-0001-9837-805X
University of California, Irvine · US

Funding

Photonics Monitoring and Modeling CoreU54ES027698 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI WHITE, CARL W · 2016 to 2021
$16.7M
Training Program in Cardiovascular Applied Research and EntrepreneurshipT32HL116270 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI HUGHES, CHRISTOPHER C. W. · 2013 to 2022
$1.6M
NHLBI NIH HHS T32 HL116270NIEHS NIH HHS U54 ES027698
6 · The paper itself

Abstract

Molecular sensors from protein engineering offer new methods to sensitively bind to and detect target analytes for a wide range of applications. For example, these sensors can be integrated into probes for implantation, and then yield new and valuable physiological information. Here, a new Förster resonance energy transfer (FRET)-based sensor is integrated with an optical fiber to yield a device measuring free Ca

Indexed as

Fluorescence Resonance Energy TransferAnimalsBatrachoidiformesCalciumPhotochemical ProcessesProteolysisTroponin CCalciumTroponin C

Identifiers

PMID32352281
PMCPMC7316412
OpenAlexW3022676722

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.