Evidence map›Paper›PMID 32352184›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Enantioselective S-H Insertion Reactions of α-Carbonyl Sulfoxonium Ylides.

Patrícia B Momo, Alexandria N Leveille, Elliot H E Farrar, Matthew N Grayson, Anita E Mattson, Antonio C B Burtoloso

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  7. Review
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  10. Article
  11. Dearomatization of benzopyrylium triflates with sulfoxonium ylides.Chemical communications (Cambridge, England) · 2022
    Article
  12. Article
  13. Synthesis of INature communications · 2022
    Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Patrícia B MomoInstitute of Chemistry of São Carlos, University of São Paulo, CEP 13560-970, São Carlos, SP, Brazil.
Alexandria N LeveilleDepartment Chemistry and Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA, 01609, USA.
Elliot H E FarrarDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.
Matthew N GraysonDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK.
Anita E MattsonDepartment Chemistry and Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA, 01609, USA.
Antonio C B BurtolosoInstitute of Chemistry of São Carlos, University of São Paulo, CEP 13560-970, São Carlos, SP, Brazil.ORCID http://orcid.org/0000-0003-2203-1556

Funding

Silanediol Enabled Drug DiscoveryR35GM124804 · NIGMS · WORCESTER POLYTECHNIC INSTITUTE · PI MATTSON, ANITA E · 2017 to 2021
$2.0M
Foundation for the National Institutes of Health 5 R35 GM124804Fundação de Amparo à Pesquisa do Estado de São Paulo 2013/18009-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/23329-9Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/19105-0NIGMS NIH HHS R35 GM124804
6 · The paper itself

Abstract

The first example of enantioselective S-H insertion reactions of sulfoxonium ylides is reported. Under the influence of thiourea catalysis, excellent levels of enantiocontrol (up to 95 % ee) and yields (up to 97 %) are achieved for 31 examples in S-H insertion reactions of aryl thiols and α-carbonyl sulfoxonium ylides.

Indexed as

aryl thiolenantioselectivityorganocatalysisS−H insertionsulfoxonium ylide

Identifiers

PMID32352184
PMCPMC7606806

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.