Evidence map›Paper›PMID 32352037›Full record

ArticleNPJ digital medicine2020

Weak supervision as an efficient approach for automated seizure detection in electroencephalography.

Khaled Saab, Jared Dunnmon, Christopher Ré, Daniel Rubin, Christopher Lee-Messer

Abstract read
In one paragraph

Article in NPJ digital medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Review
  6. Article
  7. Article
  8. An Implantable Device that Converses with Patients and Learns to Co-Manage Epilepsy.medRxiv : the preprint server for health sciences · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Using artificial intelligence to optimize anti-seizure treatment and EEG-guided decisions in severe brain injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  14. Dynamic GNNs for Precise Seizure Detection and Classification from EEG Data.Advances in knowledge discovery and data mining : ... Pacific-Asia Conference, PAKDD ..., proceedings. Pacific-Asia Conference on Knowledge Discovery and Data Mining · 2024
    Article
  15. Article
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  19. Assisting schizophrenia diagnosis using clinical electroencephalography and interpretable graph neural networks: a real-world and cross-site study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Khaled Saab *1Department of Electrical Engineering, Stanford University, Stanford, CA USA.ORCID 0000-0003-1427-0469
Jared Dunnmon *2Department of Computer Science, Stanford University, Stanford, CA USA.
Christopher Ré2Department of Computer Science, Stanford University, Stanford, CA USA.
Daniel Rubin *3Department of Biomedical Data Science, Stanford University, Stanford, CA USA.ORCID 0000-0001-5057-4369
Christopher Lee-Messer *4Department of Child Neurology, Stanford University, Stanford, CA USA.ORCID 0000-0002-2938-6184

Funding

Training CoreU54EB020405 · NIBIB · STANFORD UNIVERSITY · PI DELP, SCOTT L · 2014 to 2018
$11.6M
NIBIB NIH HHS U54 EB020405
6 · The paper itself

Abstract

Automated seizure detection from electroencephalography (EEG) would improve the quality of patient care while reducing medical costs, but achieving reliably high performance across patients has proven difficult. Convolutional Neural Networks (CNNs) show promise in addressing this problem, but they are limited by a lack of large labeled training datasets. We propose using imperfect but plentiful archived annotations to train CNNs for automated, real-time EEG seizure detection across patients. While these weak annotations indicate possible seizures with precision scores as low as 0.37, they are commonly produced in large volumes within existing clinical workflows by a mixed group of technicians, fellows, students, and board-certified epileptologists. We find that CNNs trained using such weak annotations achieve Area Under the Receiver Operating Characteristic curve (AUROC) values of 0.93 and 0.94 for pediatric and adult seizure onset detection, respectively. Compared to currently deployed clinical software, our model provides a 31% increase (18 points) in F1-score for pediatric patients and a 17% increase (11 points) for adult patients. These results demonstrate that weak annotations, which are sustainably collected via existing clinical workflows, can be leveraged to produce clinically useful seizure detection models.

Indexed as

Computer scienceEpilepsy

Identifiers

PMID32352037
PMCPMC7170880

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.