Evidence map›Paper›PMID 32352001›Full record

ArticleBioMed research international2020

Biomimetic Gold Nanoshell-Loaded Macrophage for Photothermal Biomedicine.

Sung Hun Kang, Yong Kyu Lee, Il Seok Park, In-Kyu Park, Seok Min Hong, Soon Young Kwon, Young Hee Choi, Steen J Madsen, Henry Hirschberg, Seok Jin Hong

Abstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Pathogens and global health · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Photothermal conversion of SiORSC advances · 2020
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sung Hun KangDepartment of Biomedical Sciences, College of Medicine, Hallym University, Chuncheon 24252, Republic of Korea.
Yong Kyu LeeDepartment of Chemical and Biological Engineering, Korea National University of Transportation, Chungju 27469, Republic of Korea.
Il Seok ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, Hallym University, Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, Gyeonggi-do, Republic of Korea 18450.
In-Kyu ParkDepartment of Biomedical Sciences, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.ORCID https://orcid.org/0000-0002-8522-8236
Seok Min HongDepartment of Otorhinolaryngology-Head and Neck Surgery, Hallym University, Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, Gyeonggi-do, Republic of Korea 18450.
Soon Young KwonDepartment of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Ansan, Republic of Korea.
Young Hee ChoiDepartment of Pathology, Hallym University, Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, Gyeonggi-do, Republic of Korea 18450.
Steen J MadsenDepartment of Health Physics and Diagnostic Sciences, University of Nevada, Las Vegas 4505 S. Maryland Pkwy, Las Vegas, NV 89154-3037, USA.
Henry HirschbergBeckman Laser Institute and Medical Clinic, University of California, Irvine 1002 Health Sciences Rd, Irvine, CA 92617, USA.
Seok Jin HongDepartment of Otorhinolaryngology-Head and Neck Surgery, Hallym University, Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, Gyeonggi-do, Republic of Korea 18450.ORCID https://orcid.org/0000-0002-9061-0552

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to investigate the effect of photothermal treatment (PTT) with gold nanoshell (ANS) using a macrophage-mediated delivery system in a head and neck squamous cell carcinoma (HNSCC) cell line. To achieve this, ANS-loaded rat macrophages (ANS-MAs) were prepared via the coculture method with ANS. The human HNSCC (FaDu cell) and macrophage (rat macrophage; NR8383 cell) hybrid spheroid models were generated by the centrifugation method to determine the possibility of using ANS-MAs as a cancer therapy. These ANS-MAs were set into the tumor and macrophage hybrid spheroid model to measure PTT efficacy. Kinetic analysis of the spheroid growth pattern revealed that this PTT process caused a decreasing pattern in the volume of the hybrid model containing ANS-MAs (

Indexed as

GoldHyperthermia, InducedNanoshellsSquamous Cell Carcinoma of Head and NeckAnimalsCell Line, TumorHumansMacrophagesRatsRats, Sprague-DawleyGold

Identifiers

PMID32352001
PMCPMC7178525

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.