Evidence map›Paper›PMID 32351982›Full record

ArticleInternational journal of genomics2020

An Integrated Approach Exploring the Synergistic Mechanism of Herbal Pairs in a Botanical Dietary Supplement: A Case Study of a Liver Protection Health Food.

Liang Chen, Chun Hu, Molly Hood, Juntao Kan, Xiaona Gan, Xue Zhang, Yi Zhang, Jun Du

Open access · goldAbstract read
In one paragraph

Article in International journal of genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  7. Plants (Basel, Switzerland) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Liang ChenNutrilite Health Institute, 720 Cailun Road, Shanghai 201203, China.ORCID https://orcid.org/0000-0001-7434-4461
Chun HuNutrilite Health Institute, 5600 Beach Boulevard, Buena Park, CA 90621, USA.
Molly HoodNutrilite Health Institute, 7575 East Fulton Avenue, Ada, MI 49355, USA.
Juntao KanNutrilite Health Institute, 720 Cailun Road, Shanghai 201203, China.ORCID https://orcid.org/0000-0001-7280-6394
Xiaona GanNutrilite Health Institute, 720 Cailun Road, Shanghai 201203, China.
Xue ZhangNutrilite Health Institute, 720 Cailun Road, Shanghai 201203, China.
Yi ZhangNutrilite Health Institute, 720 Cailun Road, Shanghai 201203, China.
Jun DuNutrilite Health Institute, 720 Cailun Road, Shanghai 201203, China.ORCID https://orcid.org/0000-0001-5640-0853
Mercy Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herbal pairs are used as a bridge between single herb and polyherbal formulas in Traditional Chinese Medicine (TCM) to provide rationale for complicated TCM formulas. The effectiveness and rationality of TCM herbal pairs have been widely applied as a strategy for dietary supplements. However, due to the complexity of the phytochemistry of individual and combinations of herbal materials, it is difficult to reveal their effective and synergistic mechanisms from a molecular or systematic point of view. In order to address this question, UPLC-Q-TOF/MS analysis and System Pharmacology tools were applied to explore the mechanism of action, using a White Peony (

Identifiers

PMID32351982
PMCPMC7171619
OpenAlexW3015228525

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.