ArticleCureus2020
Thyroid Nodule Size and Prediction of Cancer: A Study at Tertiary Care Hospital in Saudi Arabia.
Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of thyroid disorders in inland and coastal populations: A systematic review.Frontiers in endocrinology · 2026Pooled it
- Pooled it
- Precision medicine in thyroid nodules: current strategies, challenges, and future directions.Hormones (Athens, Greece) · 2026Review
- Article
- Surgical outcomes of Bethesda System for Reporting Thyroid Cytopathology diagnostic category class I, II, and III thyroid nodules.Frontiers in endocrinology · 2026Article
- Quantitative Ultrasound Grayscale Analysis and Size of Benign and Malignant Solid Thyroid Nodules.Tomography (Ann Arbor, Mich.) · 2025Article
- Characterization of Medical Neck Palpation to Inform Design of Haptic Palpation Sensors.Sensors (Basel, Switzerland) · 2025Article
- Multicenter Evaluation of Thyroid Nodule Size: Implications for FNA Diagnostic Accuracy and Malignancy Risk.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2025Article
- A cascaded clinical-ultrasound-biochemical model for precise prediction before thyroid nodule fine-needle aspiration biopsy.Frontiers in medicine · 2025Article
- High Malignancy Risk and Its Predictors in South Indian Patients With Bethesda II Thyroid Nodules.Cureus · 2024Article
- Emerging therapeutic options for follicular-derived thyroid cancer in the era of immunotherapy.Frontiers in immunology · 2024Review
- Clinical, cytological and ultrasonographic features of incidental thyroid cancer in a hospital-based study in vietnam.Endocrinology, diabetes & metabolism · 2023Article
- Predictors and a prediction model for positive fine needle aspiration biopsy in C-TIRADS 4 thyroid nodules.Frontiers in endocrinology · 2023Article
- Clinico-cytopathological subcategorization in thyroid nodules of atypia of undetermined significance/follicular lesion of undetermined significance using the TIRADS and Bethesda classifications.Frontiers in endocrinology · 2023Article
- Patterns of Thyroid Cancer Mortality and Incidence in Saudi Arabia: A 30-Year Study.Diagnostics (Basel, Switzerland) · 2022Article
- Cytological patterns of thyroid lesions in Najran, Saudi Arabia: A 5-year retrospective study.Saudi medical journal · 2022Article
- Characterization of focal hypermetabolic thyroid incidentaloma: An analysis with F-18 fluorodeoxyglucose positron emission tomography/computed tomography parameters.World journal of clinical cases · 2022Article
- Surgical Outcome and Malignant Risk Factors in Patients With Thyroid Nodule Classified as Bethesda Category III.Frontiers in endocrinology · 2021Article
- Different sonographic features of peripheral thyroid nodule calcification and risk of malignancy: a prospective observational study.Polish journal of radiology · 2021Article
- A Review of the Pathology, Diagnosis and Management of Colloid Goitre.European endocrinology · 2020Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Thyroid noduleshave become relatively common in clinical practice,and their prevalence increases with age. The majority of thyroid nodules are benign, with 5-15% being malignant. There are a number of well-established predictors of malignancy in thyroid nodules, but thyroid nodule size has been a cause for concern for many researchers and results of the studies are still controversial about their probability of malignancy. Up to the current knowledge, there is no published study that evaluates if thyroid nodule size is associated with the risk of malignancy in Saudi Arabia, so in this study, we aim to find that. Methods This is a retrospective study of 987 patients who underwent thyroid nodule fine-needle aspiration (FNA) and subsequent thyroidectomy for thyroid nodules measuring ≥ 1 cm. Results Thyroid cancer was more prevalent in males than females, and in patients who were older than or equal to 45 years. Nodular size of 1 - 1.9 cm was more prevalent among cancer patients than in benign cases (p<0.001). Conclusions The highest malignancy risk was observed in nodules <2 cm and no increase in malignancy risk for nodules >2 cm. Nevertheless, when examined by type of thyroid malignancy, the rate of follicular carcinoma and other rare malignancy increased with increasing nodule size.
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