Evidence map›Paper›PMID 32351709›Full record

ArticleNPJ genomic medicine2020

Erlotinib sensitivity of

Hoi-Lam Ngan, Peony Hiu Yan Poon, Yu-Xiong Su, Jason Ying Kuen Chan, Kwok-Wai Lo, Chun Kit Yeung, Yuchen Liu, Eileen Wong, Hui Li, Chin Wang Lau and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ genomic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Hoi-Lam Ngan *School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Peony Hiu Yan Poon *School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Yu-Xiong Su2Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, Hong Kong.
Jason Ying Kuen ChanDepartment of Otorhinolaryngology, Head & Neck Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.ORCID 0000-0002-9480-4637
Kwok-Wai LoDepartment of Anatomical and Cellular Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Chun Kit YeungSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Yuchen LiuSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Eileen WongSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Hui LiSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Chin Wang Lau5Department of Otorhinolaryngology Head and Neck, Yan Chai Hospital, Hong Kong SAR, Hong Kong.
Wenying PiaoSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.
Vivian Wai Yan LuiSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong.ORCID 0000-0001-6918-1573
Chinese University of Hong Kong · HKUniversity of Hong Kong · HKYan Chai Hospital · HK

Funding

qHTS of Patient Derived HCC Models to Identify Novel Probes/Therapeutic AgentsR01CA229836 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHNSTON, PAUL A. · 2019 to 2022
$1.8M
Food and Health Bureau of the Government of the Hong Kong Special Administrative Region | Health and Medical Research Fund (HMRF) 15160691Innovation and Technology Fund (ITF) PIH/052/18Innovation and Technology Fund (ITF) PIH/234/18Innovation and Technology Fund (ITF) UIM/329NCI NIH HHS R01 CA229836Research Grants Council, University Grants Committee (RGC, UGC) 14108818Research Grants Council, University Grants Committee (RGC, UGC) 14109716Research Grants Council, University Grants Committee (RGC, UGC) 14168517Research Grants Council, University Grants Committee (RGC, UGC) 17114814Research Grants Council, University Grants Committee (RGC, UGC) 17120718Research Grants Council, University Grants Committee (RGC, UGC) 17121616Research Grants Council, University Grants Committee (RGC, UGC) R4017-18U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) 1R01CA229836-01A1
6 · The paper itself

Abstract

Head and neck squamous cell carcinoma (HNSCC) lacks predictive biomarkers for drug responses. By targeted sequencing, we identified two

Indexed as

Cancer geneticsHead and neck cancerTargeted therapies

Identifiers

PMID32351709
PMCPMC7171136
OpenAlexW3016407441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.