Evidence map›Paper›PMID 32351680›Full record

ArticleJournal of thyroid research2020

Prognostic Significance of Thyroglobulin Antibodies in Differentiated Thyroid Cancer.

Jordi L Reverter, Irene Rosas-Allende, Carlos Puig-Jove, Carles Zafon, Ana Megia, Ignasi Castells, Eduarda Pizarro, Manel Puig-Domingo, M Luisa Granada

Open access · hybridAbstract read
In one paragraph

Article in Journal of thyroid research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jordi L ReverterDepartments of Endocrinology and Nutrition, Germans Trias i Pujol Hospital and Research Institute, Universitat Autònoma de Barcelona, CIBERER (ISCIII), Barcelona, Spain.ORCID https://orcid.org/0000-0003-0362-2035
Irene Rosas-AllendeClinical Biochemistry, Germans Trias i Pujol Hospital and Research Institute, Universitat Autònoma de Barcelona, CIBERER (ISCIII), Barcelona, Spain.
Carlos Puig-JoveDepartments of Endocrinology and Nutrition, Germans Trias i Pujol Hospital and Research Institute, Universitat Autònoma de Barcelona, CIBERER (ISCIII), Barcelona, Spain.
Carles ZafonConsortium for the Study of Thyroid Cancer, CECAT, Barcelona, Spain.
Ana MegiaConsortium for the Study of Thyroid Cancer, CECAT, Barcelona, Spain.
Ignasi CastellsConsortium for the Study of Thyroid Cancer, CECAT, Barcelona, Spain.
Eduarda PizarroConsortium for the Study of Thyroid Cancer, CECAT, Barcelona, Spain.
Manel Puig-DomingoDepartments of Endocrinology and Nutrition, Germans Trias i Pujol Hospital and Research Institute, Universitat Autònoma de Barcelona, CIBERER (ISCIII), Barcelona, Spain.
M Luisa GranadaConsortium for the Study of Thyroid Cancer, CECAT, Barcelona, Spain.
Universitat Autònoma de Barcelona · ESHospital de Mataró · ESHospital General de Granollers · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate whether variations in thyroglobulin autoantibodies (TgAb) are related to the recurrence or persistence of differentiated thyroid carcinoma (DTC) and may therefore be useful as surrogate tumor markers.

resultsIn the group of 11 patients with stable TgAb, four cases presented persistence of the disease with structural incomplete response. In the group of 22 patients with sustained increasing trend rising more than 50% or

conclusionsOur results suggest that not only the appearance of a significant increase in TgAb but also stable concentrations of TgAb should be regarded as a sufficient risk condition for an active search for recurrent or persistent disease. Conversely, a significant decrease in TgAb levels can represent a good prognostic sign.

Identifiers

PMID32351680
PMCPMC7178500
OpenAlexW3016380224

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.