Evidence map›Paper›PMID 32351606›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Evaluation of the Antidiarrheal Activity of Hydromethanol Crude Extracts of

Amsalu Degu, Belayneh Kefale, Diriba Alemayehu, Gobezie Temesgen Tegegne

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  6. Evaluation of Antidiarrheal Activity of 80% Methanol Extract and Solvent Fractions of the Leaves ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  7. Evaluation ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  8. Methanolic Crude Extract ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Amsalu DeguSchool of Pharmacy and Health Sciences, United States International University-Africa, Nairobi, Kenya.ORCID https://orcid.org/0000-0002-6562-0548
Belayneh KefaleDepartment of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Diriba AlemayehuDepartment of Pharmacy, College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia.ORCID https://orcid.org/0000-0001-7047-2394
Gobezie Temesgen TegegneDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.ORCID https://orcid.org/0000-0001-7347-7561
Addis Ababa University · ETAlliant International University · USAmbo University · ETDebre Tabor University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe herbal medicine practitioners in Ethiopia have used a wide range of medicinal plants as antidiarrheal agents. Among these,

methodsThe crude extracts were obtained by cold maceration with 80% methanol, and its antidiarrheal activities were evaluated using a castor oil-induced diarrheal model. The test groups were treated with 100, 200, and 400 mg/kg body weight (bw) of the crude extract of each plant, while the positive controls and negative controls were given loperamide (3 mg/kg.bw) and 2% Tween 80 (10 ml/kg.bw), respectively.

resultsIn the castor oil-induced model, the crude extract of

conclusionThe present study demonstrated that the crude leaves extract of

Identifiers

PMID32351606
PMCPMC7174968
OpenAlexW3015891289

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.