Evidence map›Paper›PMID 32351419›Full record

ArticleFrontiers in psychiatry2020

Proxy WHO Disability Assessment Schedule 2.0 Is Clinically Useful for Assessing Psychosocial Functioning in Severe Mental Illness.

Anne B Koopmans, Daphne van Hoeken, Diana E Clarke, David J Vinkers, Peter N van Harten, Hans W Hoek

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02713672 (Cost-effectiveness of CYP2D6 and CYP2C19 Genotyping in Psychiatric Patients in Curacao), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02713672 nacompletednot on this map

Cost-effectiveness of CYP2D6 and CYP2C19 Genotyping in Psychiatric Patients in Curacao

TypeinterventionalSponsorGGZ CentraalRan2014 to 2015Enrolled86ConditionsCYP2D6, Psychiatric PatientsArmsDose adjustment according to genotype
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anne B KoopmansParnassia Academy, Parnassia Psychiatric Institute, The Hague, Netherlands.
Daphne van HoekenParnassia Academy, Parnassia Psychiatric Institute, The Hague, Netherlands.
Diana E ClarkeDivision of Research, American Psychiatric Association, Arlington, VA, United States.
David J VinkersSchool for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.
Peter N van HartenSchool for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.
Hans W HoekParnassia Academy, Parnassia Psychiatric Institute, The Hague, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study explores how well the World Health Organization Disability Assessment Schedule (WHODAS 2.0) assesses problems with psychosocial functioning in patients with severe mental illness (SMI). Further, we assessed the relationships between psychosocial functioning and psychopathology, medication side effects, treatment setting, and quality of life.

methodsWe performed an observational, cross-sectional study on the island of Curaçao to assess psychosocial functioning in 77 patients with SMI; they mainly had psychotic disorders. We interviewed their healthcare providers using the proxy version of the WHODAS 2.0. In addition, patients were examined for psychiatric symptoms, medication side effects (including drug-induced movement disorders), and quality of life. Associations were examined with Spearman's rank correlation (ρ).

resultsDifficulties in psychosocial functioning were reported by patients with SMI in the WHODAS 2.0 domains of understanding and communicating [mean (M)=34.5, standard deviation (SD)=18.6), participation in society (M=25.5, SD=15.6), and getting along with people (M=24.1, SD=16.1)]. Notably, outpatients had more problems participating in society than inpatients (M=33.6, SD=18.5

conclusionThe proxy version of the WHODAS 2.0 is clinically useful for patients with severe mental illness. The highest scores on the WHODAS 2.0 were found in domains related to interactions with other people and to participation in society. Inpatient status appeared to aid participation in society; this might be due to living in the sheltered clinic environment and its associated daily activities. We further found that drug-induced parkinsonism was associated with a broad spectrum of psychosocial disabilities. CLINICAL

trial registrationClinicalTrials.gov, identifier: NCT02713672; retrospectively registered in February 2016.

Indexed as

Caribbeanfunctioningrecoveryrehabilitationschizophreniasevere mental illnessWHO Disability Assessment Schedule

Identifiers

PMID32351419
PMCPMC7174765

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